Gao X, Zhang J, Zhang L
Institute of Economics and Technology, University of Science and Technology, Hefei 230052, China.
Wei Sheng Yan Jiu. 2000 Jan 30;29(1):57-8.
The reaction ratio of nano red elemental selenium (nanose) with GSH in vitro was one-tenth of that of sodium selenite. Mice were fed with nanose and sodium selenite separately at 50 micrograms/kg BW for 30 days. Both selenium forms could significantly increased Se concentration of blood, liver and activity of blood GSH-Px. Acute toxicity experiment of mice implied that the acute toxicity of nanose was nearly one-seventh of that of sodium selenite. The LD50 for nanose se was 112.98 mg kg BW, and the LD50 for sodium selenite was Se 15.72 mg/kg BW. The acute toxicity of nanose was low for mice.
纳米红色元素硒（nanose）与谷胱甘肽（GSH）在体外的反应比是亚硒酸钠的十分之一。将小鼠分别以50微克/千克体重的剂量喂食纳米红色元素硒和亚硒酸钠，持续30天。两种硒形态均可显著提高血液、肝脏中的硒浓度以及血液中谷胱甘肽过氧化物酶（GSH-Px）的活性。小鼠急性毒性实验表明，纳米红色元素硒的急性毒性约为亚硒酸钠的七分之一。纳米红色元素硒的半数致死量（LD50）为112.98毫克/千克体重，亚硒酸钠的LD50为15.72毫克/千克体重。纳米红色元素硒对小鼠的急性毒性较低。
