Ohashi Naro, Isozaki Taisuke, Shirakawa Kentaro, Ikegaya Naoki, Yamamoto Tatsuo, Hishida Akira
Division of Nephrology, Seirei Hamamatsu General Hospital, Hamamatsu.
Intern Med. 2003 Apr;42(4):362-6. doi: 10.2169/internalmedicine.42.362.
We report a woman with lupus nephritis complicated with lupus peritonitis and cytomegalovirus (CMV) colitis. Diagnosis of lupus peritonitis was made by abdominal computed tomography scan, colonoscopy, and ascitic fluid analysis. Steroid and cyclophosphamide therapy resulted in the improvement of severe lupus nephritis and peritonitis. Thereafter, she developed multiple colonic ulcers as diagnosed by colonoscopy and positive CMV antigenemia assay. Treatment with ganciclovir resulted in the disappearance of colonic lesions. The low cluster of differentiation (CD)4+ lymphocyte count (41/mm3) suggested that the cell-mediated immunity of this patient was comparable to that seen in patients with acquired immunodeficiency syndrome (AIDS).
我们报告了一名患有狼疮性肾炎并伴有狼疮性腹膜炎和巨细胞病毒（CMV）结肠炎的女性。狼疮性腹膜炎通过腹部计算机断层扫描、结肠镜检查和腹水分析得以诊断。类固醇和环磷酰胺治疗使严重的狼疮性肾炎和腹膜炎得到改善。此后，经结肠镜检查和CMV抗原血症检测呈阳性，她出现了多处结肠溃疡。更昔洛韦治疗使结肠病变消失。低分化簇（CD）4+淋巴细胞计数（41/mm³）表明该患者的细胞介导免疫与获得性免疫缺陷综合征（AIDS）患者相当。
