1岁以下儿童的脑肿瘤：着重探讨预后因素的关系
Brain tumors in children under 1 year of age: emphasis on the relationship of prognostic factors.
作者信息
Rivera-Luna Roberto, Medina-Sanson Aurora, Leal-Leal Carlos, Pantoja-Guillen Francisco, Zapata-Tarrés Marta, Cardenas-Cardos Rocio, Barrera-Gómez Rafael, Rueda-Franco Fernando
机构信息
Department of Oncology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, 04530, Mexico City, Mexico.
出版信息
Childs Nerv Syst. 2003 Jun;19(5-6):311-4. doi: 10.1007/s00381-003-0738-9. Epub 2003 May 6.
OBJECTS
Primary brain tumors in infants under 12 months of age have a different prognosis from older children.
MATERIAL
A retrospective analysis was done in all patients less than 12 months old with primary brain tumors.
RESULTS
Out of 1682 children with primary brain tumors, 61 (3.6%) were infants under 12 months old. The mean age at diagnosis was 181.6 days (SD 128) with a range of 1 to 364 days. There were 37 males (60.6%). The most common tumor was astrocytoma ( n=22) (36%). Supratentorial tumors were present in 63.9% but this was not related to survival ( p=0.1095). Complete surgical resection ( n=14) was favorable for survival ( p=0.039). Intracranial hypertension at diagnosis did not influence survival ( p=0.89). The overall survival rate was 32%, mean 42.08 (SD 7.38). A total of 24 patients are alive and without evidence of disease.
CONCLUSION
Complete surgical resection was necessary for a favorable prognosis, and the long-term effects are a valid problem.
目的
12个月以下婴儿的原发性脑肿瘤预后与大龄儿童不同。
材料
对所有12个月以下患有原发性脑肿瘤的患者进行回顾性分析。
结果
在1682例原发性脑肿瘤患儿中，61例（3.6%）为12个月以下的婴儿。诊断时的平均年龄为181.6天（标准差128），范围为1至364天。男性37例（60.6%）。最常见的肿瘤是星形细胞瘤（n = 22）（36%）。幕上肿瘤占63.9%，但这与生存率无关（p = 0.1095）。完整手术切除（n = 14）有利于生存（p = 0.039）。诊断时的颅内高压不影响生存（p = 0.89）。总生存率为32%，平均42.08（标准差7.38）。共有24例患者存活且无疾病证据。
结论
完整手术切除对良好预后是必要的，长期影响是一个值得关注的问题。
Zotero 插件