Jeng Chii, Chang Wen, Wai Pui Man, Chou Chen-Liang
Taipei Medical University, School of Nursing, Taoyuan, Taiwan.
Heart Lung. 2003 Mar-Apr;32(2):121-30. doi: 10.1067/mhl.2003.20.
The purposes of this study were to compare the daily activity oxygen consumption (VO(2)) and peak oxygen consumption (VO(2peak)) for chronic obstructive pulmonary disease (COPD) patients and healthy individuals; to compare dyspnea levels found in COPD patients and healthy individuals when they performed daily activities and exercise tests; and to establish standard VO(2) values for daily activities for COPD patients.
This was an exploratory and correlative study.
The study took place at the Research Center of Sports Medicine at Taipei Medical University, in Taipei, Taiwan.
The study included 27 COPD patients and 18 healthy subjects whose ages, weights, and heights were matched.
VO(2peak) and the VO(2) for performing daily activities including sitting, standing, walking, walking with a 2-kg load, and walking upstairs for 2 stories.
All data were collected by means of questionnaires and treadmill exercise tests. VO(2) was measured using an AEROSPORT KB1-C metabolic measurement system.
There was no significant difference in VO(2) found between the 2 groups when they were performing daily activities, but the VO(2peak) was significantly lower in the COPD group (13.90 +/- 2.93 mL kg(-1) min(-1)) compared with the healthy control group (16.15 +/- 1.86 mL kg(-1) min(-1)) (P =.01). The dyspnea level of the COPD group when they were performing daily activities and exercise tests was more severe than that of the healthy control group. The mean VO(2) values for daily activities in COPD patients were as follows: sitting 3.41 (+/-0.82), standing 3.67 (+/-0.90), walking 10.06 (+/-2.19), walking with a 2-kg load 10.28, and walking upstairs 8.16 (+/-1.36) mL kg(-1) min(-1).
The results of this study reveal that there were no differences in VO(2) values for performing daily activities between COPD patients and healthy individuals. However, an increase in dyspnea level occurred during daily activities, and it was found to be more severe for COPD patients than for healthy individuals. A key factor was probably that COPD patients had an obviously lower VO(2peak) and higher relative exercise intensity for daily activities than did healthy individuals.
本研究旨在比较慢性阻塞性肺疾病（COPD）患者与健康个体的日常活动耗氧量（VO₂）和峰值耗氧量（VO₂peak）；比较COPD患者与健康个体在进行日常活动和运动测试时的呼吸困难程度；并建立COPD患者日常活动的标准VO₂值。
这是一项探索性和相关性研究。
研究在台湾台北市台北医学大学运动医学研究中心进行。
该研究纳入了27名COPD患者和18名年龄、体重和身高相匹配的健康受试者。
VO₂peak以及进行日常活动（包括坐、站、行走、负重2千克行走和上两层楼梯）时的VO₂。
所有数据通过问卷调查和跑步机运动测试收集。VO₂使用AEROSPORT KB1 - C代谢测量系统进行测量。
两组在进行日常活动时VO₂无显著差异，但COPD组的VO₂peak（13.90±2.93毫升·千克⁻¹·分钟⁻¹）显著低于健康对照组（16.15±1.86毫升·千克⁻¹·分钟⁻¹）（P = 0.01）。COPD组在进行日常活动和运动测试时的呼吸困难程度比健康对照组更严重。COPD患者日常活动的平均VO₂值如下：坐3.41（±0.82）、站3.67（±0.90）、行走10.06（±2.19）、负重2千克行走10.28以及上两层楼梯8.16（±1.36）毫升·千克⁻¹·分钟⁻¹。
本研究结果表明，COPD患者与健康个体在日常活动的VO₂值方面没有差异。然而，日常活动期间呼吸困难程度增加，且发现COPD患者比健康个体更严重。一个关键因素可能是COPD患者的VO₂peak明显低于健康个体，且日常活动的相对运动强度更高。
