Cupero Timothy M, Kim Sam Y, Silva Andrew B
Department of Otolaryngology-Head and Neck Surgery, Madigan Army Medical Center, Tacoma, Wash., USA.
Ear Nose Throat J. 2003 Apr;82(4):305-8.
We conducted a placebo-controlled, single-blind study to determine the efficacy of a local preoperative injection of a steroid/anesthetic combination in preventing post-tonsillectomy pain. We randomized 21 adults to receive either triamcinolone/bupivacaine on the left side and saline on the right or vice versa. Injections were administered in the area of the tonsillar pillars following intubation and prior to tonsillectomy. Based on the "generalized estimating equations" model of statistical analysis, we found no significant difference in the degree of postoperative pain between the active-treatment and control sides.
我们进行了一项安慰剂对照的单盲研究，以确定术前局部注射类固醇/麻醉剂组合预防扁桃体切除术后疼痛的疗效。我们将21名成年人随机分组，使其一侧接受曲安奈德/布比卡因注射，另一侧接受生理盐水注射，左右侧可互换。在插管后及扁桃体切除术前，于扁桃体柱区域进行注射。基于统计分析的“广义估计方程”模型，我们发现积极治疗侧与对照侧术后疼痛程度无显著差异。
