Hegarty Kelsey, Ames David, Anderson Jeremy, Johnson Caroline, McKinnon Roslyn, Moulds Rob
Department of General Practice, University of Melbourne, Victoria.
Aust Fam Physician. 2003 Apr;32(4):229-34, 236-7, 239 passim.
Antidepressants are commonly prescribed in general practice for depression, but also for a wide range of other psychiatric conditions and physical problems.
This review, although concentrating on the use of antidepressants in depression, also reviews their use in other conditions commonly seen in general practice.
For most major depression, all antidepressant drugs have equal efficacy. The choice of antidepressant drug needs to be tailored to the particular patient's medical condition and personal preferences. It is likely that adverse effects are the major determinant in the choice of antidepressant for a particular patient. However, in treating conditions other than depression, the efficacy of the antidepressant drug can be the primary issue of drug choice.
在全科医疗中，抗抑郁药常用于治疗抑郁症，但也用于多种其他精神疾病和身体问题。
本综述虽着重于抗抑郁药在抑郁症中的应用，但也回顾其在全科医疗中常见的其他病症中的应用。
对于大多数重度抑郁症，所有抗抑郁药物疗效相当。抗抑郁药物的选择需根据特定患者的病情和个人偏好进行调整。不良反应可能是为特定患者选择抗抑郁药的主要决定因素。然而，在治疗抑郁症以外的病症时，抗抑郁药物的疗效可能是药物选择的首要问题。
