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同种抗原致敏犬淋巴细胞的二次反应。

Secondary responses of alloantigen-primed dog lymphocytes.

作者信息

Lansdorpl P M, Vriesendorp H M, Betton G R, Bijnen A B

机构信息

Laboratory for Experimental Surgery, Erasmus University, Rotterdam, The Netherlands.

出版信息

Tissue Antigens. 1980 Jan;15(1):40-6. doi: 10.1111/j.1399-0039.1980.tb00883.x.

Abstract

The usefulness of Primed Lymphocyte Typing (PLT) for recognizing Lymphocyte Defined (LD) determinants of the Major Histocompatibility Complex of the dog (DLA) was assessed in 10 separate experiments. Application of a technique described for human cell to peripheral blood lymphocytes of dogs gave reproducible, informative results. DLA LD determinants were shown to be of major importance in secondary responses of alloantigen "primed" lymphocytes, but other, a yet undefined, factors also appeared to play a role in the assay.

摘要

在10个独立实验中评估了致敏淋巴细胞分型(PLT)用于识别犬主要组织相容性复合体(DLA)的淋巴细胞定义(LD)决定簇的有效性。将一种描述用于人类细胞的技术应用于犬外周血淋巴细胞,得到了可重复的、有用的结果。结果表明,DLA LD决定簇在同种异体抗原“致敏”淋巴细胞的二次反应中起主要作用,但其他尚未明确的因素在该检测中似乎也发挥了作用。

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