Hoffman Nathan, McGee Shawn M, Hulbert John C
Department of Urologic Surgery, University of Minnesota Medical School, Minneapolis, Minnesota 55455, USA.
Urology. 2003 May;61(5):1035. doi: 10.1016/s0090-4295(02)02593-1.
A patient with a history of ingesting large quantities of an over-the-counter stimulant developed renal calculi that on further analysis, after stone passage, revealed increased amounts of ephedrine. Over the course of 7 months, all of the patient's ephedrine stones were managed successfully by alkalinization. Similar to previously reported ephedrine calculi, these stones were radiolucent on x-ray imaging, but their course was monitored on serial nonenhanced computed tomography scans. We believe this to be the first reported use of alkaline therapy for the dissolution of renal stones containing ephedrine.
一名有大量服用非处方兴奋剂病史的患者患上了肾结石。在结石排出后进一步分析发现,结石中麻黄碱含量增加。在7个月的时间里,通过碱化成功处理了该患者所有的麻黄碱结石。与之前报道的麻黄碱结石相似,这些结石在X线成像上不显影,但通过系列非增强计算机断层扫描对其病程进行了监测。我们认为这是首次报道使用碱性疗法溶解含麻黄碱肾结石。