Stone W J, Horn R G
South Med J. 1976 May;69(5):545-9. doi: 10.1097/00007611-197605000-00020.
Six patients without overt diabetes mellitus underwent renal biopsy for suspected glomerulonephritis. All were demonstrated to have diabetic glomerulosclerosis and subsequently were found to have abnormal glucose tolerance tests. Electron microscopy was critical in making the correct diagnosis in five of six patients. The reported cases represent 3% of a series of 200 patients who had a renal biopsy to evaluate possible glomerulonephritis. Renal manifestations of diabetes mellitus may antedate glycosuria and other more common presenting symptoms of this disease.
6例无明显糖尿病的患者因疑似肾小球肾炎接受了肾活检。结果显示，所有患者均患有糖尿病性肾小球硬化症，随后葡萄糖耐量试验结果异常。电子显微镜检查对6例患者中的5例做出正确诊断至关重要。报告的病例占200例因评估可能的肾小球肾炎而接受肾活检患者系列的3%。糖尿病的肾脏表现可能先于糖尿及该疾病其他更常见的症状出现。
