Marshall W G, Boatman G B, Dickerson G, Perlin A, Todd E P, Utley J R
Surgery. 1976 Jun;79(6):631-7.
The shunting, release, and transmural distribution of 9 and 15 mu radioactive microspheres were compared in isolated hearts and intact hearts with and without adenosine triphosphate (ATP) vasodilation. ATP vasodilation caused increase shunting of 9 mu spheres but not 15 mu spheres (p less than 0.05). The transmural distribution of 9 and 15 mu spheres in left ventricle and septum were significantly different (p less than 0.01) and the difference was characteristic for the isolated heart and the nonvasodilated intact heart. There was no difference in distribution across the right ventricle. There appear to be significant differences in regional shunting as well as distribution in the intact heart. We found no systematic correction for comparing flows measured with 9 and 15 mu spheres.
在有和没有三磷酸腺苷(ATP)血管舒张作用的离体心脏和完整心脏中,比较了9微米和15微米放射性微球的分流、释放及透壁分布情况。ATP血管舒张导致9微米微球的分流增加,但15微米微球未增加(p<0.05)。左心室和室间隔中9微米和15微米微球的透壁分布有显著差异(p<0.01),且这种差异在离体心脏和未进行血管舒张的完整心脏中具有特征性。右心室的分布没有差异。完整心脏的区域分流和分布似乎也存在显著差异。我们没有找到用于比较用9微米和15微米微球测量的血流的系统校正方法。