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用番泻叶、马缨丹和刺冠果叶提取物治疗牛皮肤嗜皮菌病。

Treatment of bovine dermatophilosis with Senna alata, Lantana camara and Mitracarpus scaber leaf extracts.

作者信息

Ali-Emmanuel N, Moudachirou M, Akakpo J A, Quetin-Leclercq J

机构信息

Collège Polytechnique Universitaire, Université d'Abomey Calavi, 01 BP 2009 Cotonou, Benin.

出版信息

J Ethnopharmacol. 2003 Jun;86(2-3):167-71. doi: 10.1016/s0378-8741(03)00054-0.

Abstract

This study describes interesting preliminary results on the therapeutic effects of ointments prepared with extracts of medicinal plants on bovine dermatophilosis. Our results show that the use of ointments made with ethanolic extracts of leaves of Senna alata, Lantana camara and Mitracarpus scaber, as topical treatments on chronic crusty or acute lesions of dermatophilosis, induces healing of the disease in the nine infected animals treated without recurrence. This is opposed to what is observed by using oxytetracycline, terramycin long-acting (TLA), or procaine-penicillin, antibiotics commonly used parenterally for the treatment of dermatophilosis in the Republic of Benin which could not prevent the recurrence of the disease. These ointments, when applied once a day for 8-15 days, provoked the falling off of the crusts after 3-4 days of treatment. Hair grows on the treated areas, which heal without scarring, within 3-4 weeks after the end of the treatment. The healed animals became free of dermatophilosis without recurrence for more than 3 years and were in good health.

摘要

本研究描述了用药用植物提取物制备的软膏对牛皮肤嗜皮菌病治疗效果的有趣初步结果。我们的结果表明,使用由番泻叶、马缨丹和光叶米碎花叶子的乙醇提取物制成的软膏,对皮肤嗜皮菌病的慢性结痂或急性病变进行局部治疗,可使接受治疗的9只感染动物的疾病痊愈且无复发。这与使用土霉素、长效土霉素(TLA)或普鲁卡因青霉素的情况相反,这些抗生素是贝宁共和国通常用于治疗皮肤嗜皮菌病的肠胃外用药,却无法预防疾病复发。这些软膏每天涂抹一次,持续8 - 15天,在治疗3 - 4天后会促使痂皮脱落。治疗区域会长出毛发,治疗结束后3 - 4周内愈合且不留疤痕。治愈的动物在超过3年的时间里未再复发皮肤嗜皮菌病,且健康状况良好。

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