Oladeji Oluwole Solomon, Adelowo Funmilayo Enitan, Oluyori Abimbola Peter, Bankole Deborah Temitope
Natural Products Research Unit, Industrial Chemistry Programme, Department of Physical Sciences, Faculty of Pure and Applied Sciences, Landmark University, Omu-Aran, Nigeria.
Department of Pure and Applied Chemistry, Faculty of Pure and Applied Sciences, Ladoke Akintola University of Technology, PMB 4000, Ogbomoso, Nigeria.
Evid Based Complement Alternat Med. 2020 Feb 20;2020:2580259. doi: 10.1155/2020/2580259. eCollection 2020.
is a medicinal herb of Leguminosae family. It is distributed in the tropical and humid regions. The plant is traditionally used in the treatment of typhoid, diabetes, malaria, asthma, ringworms, tinea infections, scabies, blotch, herpes, and eczema. The review is aimed at unveiling the ethnobotanical description and pharmacological activities of Different parts of the plant are reported in folk medicine as therapeutic substances for remediation of diverse diseases and infections. The extracts and isolated compounds displayed pronounced pharmacological activities. Display of antibacterial, antioxidant, antifungal, dermatophytic, anticancer, hepatoprotective, antilipogenic, anticonvulsant, antidiabetic, antihyperlipidemic, antimalarial, anthelmintic, and antiviral activities could be due to the array of secondary metabolites such as tannins, alkaloids, flavonoids, terpenes, anthraquinone, saponins, phenolics, cannabinoid alkaloids, 1,8-cineole, caryophyllene, limonene, -selinene, -caryophyllene, germacrene D, cinnamic acid, pyrazol-5-ol, methaqualone, isoquinoline, quinones, reducing sugars, steroids, and volatile oils present in different parts of the plant. The review divulges the ethnobotanical and pharmacological activities of the plant and also justifies the ethnomedical claims. The significant medicinal value of this plant necessitates a scientific adventure into the bioactive metabolites which constitute various extracts.
是豆科的一种药草。它分布于热带和湿润地区。这种植物传统上用于治疗伤寒、糖尿病、疟疾、哮喘、癣、癣感染、疥疮、斑点、疱疹和湿疹。本综述旨在揭示该植物的民族植物学描述和药理活性。该植物的不同部位在民间医学中被报道为治疗多种疾病和感染的治疗物质。提取物和分离出的化合物显示出显著的药理活性。表现出抗菌、抗氧化、抗真菌、抗皮肤真菌、抗癌、保肝、抗脂肪生成、抗惊厥、抗糖尿病、抗高血脂、抗疟疾、驱虫和抗病毒活性，可能是由于该植物不同部位存在一系列次生代谢产物，如单宁、生物碱、黄酮类化合物、萜类、蒽醌、皂苷、酚类、大麻素生物碱、1,8-桉叶素、石竹烯、柠檬烯、β-瑟林烯、α-石竹烯、吉马烯D、肉桂酸、吡唑-5-醇、甲喹酮、异喹啉、醌类、还原糖、甾体和挥发油。本综述揭示了该植物的民族植物学和药理活性，并证明了民族医学的说法。这种植物的重要药用价值需要对构成各种提取物的生物活性代谢产物进行科学探索。
