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[低温排除新皮质对其颞叶区域功能保存的影响]

[The effect of cryogenic exclusion of the neocortex on preservation of the functioning of its temporal regions].

作者信息

Plekhanov V A

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1976 Jan-Feb;26(1):81-6.

PMID:1274450
Abstract

In chronic experiments on nine cats a study was made of different forms of their behavior in conditions of cold elimination of the cerebral cortex with the exception of the temporal areas. The first sessions of cooling produced a diminution of alimentary excitability, enhanced motor activity, loss of the reaction of mouse chasing and of a defensive reaction against the dog, and a disappearance of previously elaborated conditioned runnings to the feeding trough, etc. In the course of subsequent experiments with the neocortex cooling, the disturbed forms of behavior were restored. In the second and third sessions alimentary excitation was considerably restored; by the sixth and seventh sessions motor activity became normal, while the 20th to 25th sessions exhibited a protective reaction against the dog. Conditioned runnings restored in the seventinth session were manifest in the 20th to 25th sessions in 80% of cases. It is assumed that the temporal areas of the neocortex while playing a considerable part in integrating the activity of the whole brain, including the formation and manifestation of conditioned reflexes, under normal conditions, to a large extent lose their integrative role when the rest of the neocortex is elimated.

摘要

在对9只猫进行的慢性实验中,研究了除颞叶区域外大脑皮质冷消除条件下它们不同形式的行为。首次降温会使进食兴奋性降低、运动活动增强、追逐小鼠的反应和对狗的防御反应丧失,以及先前形成的到食槽的条件性奔跑等消失。在随后新皮质降温的实验过程中,受干扰的行为形式得以恢复。在第二次和第三次实验中,进食兴奋得到相当程度的恢复;到第六次和第七次实验时,运动活动恢复正常,而在第二十次到第二十五次实验中出现了对狗的防御反应。在第七十七次实验中恢复的条件性奔跑在第二十次到第二十五次实验中有80%的情况表现出来。据推测,新皮质的颞叶区域在整合整个大脑的活动,包括条件反射的形成和表现方面发挥着相当大的作用,但在正常情况下,当新皮质的其余部分被消除时,它们在很大程度上失去了整合作用。

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