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苍白球在调节皮层活动中的作用

[The role of the pallidum in regulating cortical activity].

作者信息

Sarkisian Zh S, Kazarian L G, Garibian A A, Gambarian L S

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1976 Mar-Apr;26(2):325-32.

PMID:1274464
Abstract

Bilateral ablation of the pallidum halves the duration of extinction of conditioned motor food reflexes and contributes to 30 to 50% extinction of the electro-defensive reflexes. Pallidum functional depression by potassium chloride or novacaine leads to a temporary total depression of conditioned motor food reflexes. Depending on the frequency of pallidum stimulation, synchronization or desynchronization of the cortical bioelectrical activity is observed. Ablation of the pallidum in anaesthetized cats results in a high amplitude and low-frequency cortical activity. Injection of large doses of potassium chloride into the pallidum results in a forced running forward which lasts 30 to 40 min. The pallidum is considreed as a structure controlling the cortex activity, which takes part in the mechanisms of sensory information processes in the course of adaptive behaviour.

摘要

双侧苍白球切除可使条件性运动食物反射的消退持续时间减半,并导致电防御反射消退30%至50%。用氯化钾或奴夫卡因使苍白球功能抑制会导致条件性运动食物反射暂时完全抑制。根据苍白球刺激的频率,可观察到皮质生物电活动的同步化或去同步化。麻醉猫的苍白球切除会导致高振幅和低频的皮质活动。向苍白球注射大剂量氯化钾会导致向前的强迫奔跑,持续30至40分钟。苍白球被认为是控制皮质活动的结构,它参与适应性行为过程中感觉信息处理的机制。

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