Kim Joo Yeon, Choi Dong Seong, Jung Mun Yhung
Department of Food Science and Technology, Woosuk University, Samrea-Up, Wanju-Kun, Jeonbuk Province 565-701, Republic of Korea.
J Agric Food Chem. 2003 May 21;51(11):3460-5. doi: 10.1021/jf026056p.
The effects and mechanism of sesamol on the methylene blue- or chlorophyll-sensitized photo-oxidations of soybean oil have been studied. Sesamol showed strong antiphoto-oxidative activity in both methylene blue-and chlorophyll-sensitized photo-oxidations of soybean oil in a dose-dependent manner. The 1.0 x 10(-3) M sesamol treatments showed 84.7 and 43.4% inhibitions of methylene blue- and chlorophyll-sensitized photo-oxidations of soybean oil in methylene chloride. The antiphoto-oxidative activity of sesamol was comparable to that of delta-tocopherol in both methylene blue- and chlorophyll-sensitized photo-oxidations, at the same molar basis. Sesamol effectively inhibited rubrene oxidation with a chemical source of singlet oxygen in microemulsion, showing its strong singlet oxygen quenching ability. The results suggested that the antiphoto-oxidative activity of sesamol in the photo-oxidation of oil was, at least in part, due to its singlet oxygen scavenging activity. The singlet oxygen quenching rate constant (k(ox-Q) + k(q)) of sesamol was determined to be 1.9 +/- 0.3 x 10(7) M(-1) s(-1). This represents the first report on the antiphoto-oxidative activity of sesamol in the sensitized photo-oxidation of oil, and its bimolecular singlet oxygen quenching ability.
研究了芝麻酚对亚甲基蓝或叶绿素敏化的大豆油光氧化作用的效果及机制。芝麻酚在亚甲基蓝和叶绿素敏化的大豆油光氧化过程中均表现出强烈的抗光氧化活性，且呈剂量依赖性。在二氯甲烷中，1.0×10⁻³ M芝麻酚处理对亚甲基蓝和叶绿素敏化的大豆油光氧化分别有84.7%和43.4%的抑制率。在相同摩尔基础上，芝麻酚在亚甲基蓝和叶绿素敏化的光氧化中的抗光氧化活性与δ-生育酚相当。芝麻酚在微乳液中能有效抑制由单线态氧化学源引发的红荧烯氧化，显示出其强大的单线态氧猝灭能力。结果表明，芝麻酚在油脂光氧化中的抗光氧化活性至少部分归因于其单线态氧清除活性。测定芝麻酚的单线态氧猝灭速率常数（k(ox-Q) + k(q)）为1.9±0.3×10⁷ M⁻¹ s⁻¹。这是关于芝麻酚在油脂敏化光氧化中的抗光氧化活性及其双分子单线态氧猝灭能力的首次报道。
