Darke Shane, Ross Joanne, Lynskey Michael
National Drug and Alcohol Research Center, University of New South Wales, Randwick, Australia.
Drug Alcohol Rev. 2003 Mar;22(1):21-5. doi: 10.1080/0959523021000059794.
In order to examine the effects of a diagnosis of childhood conduct disorder (CD) on history of attempted suicide and drug use, unconfounded by early onset heroin use, 181 methadone maintenance patients who commenced heroin use after the age of 15 were interviewed. CD was diagnosed in 54% of patients. Compared to other patients, CD patients were younger and less educated. The onset of drug use, injecting drug use and heroin use occurred, on average, 2 years earlier than in other patients, and they had broader histories of injecting polydrug use. CD patients were more likely to have attempted suicide and to have been hospitalized after an attempt, and to have attempted suicide while enrolled in their current treatment. The current study indicates that a history of CD increases the risk of attempted suicide over and above the higher risks associated with injecting drug use per se.
为了研究儿童品行障碍（CD）诊断对自杀未遂史和药物使用情况的影响，且不受早期使用海洛因的干扰，我们对181名15岁后开始使用海洛因的美沙酮维持治疗患者进行了访谈。54%的患者被诊断为品行障碍。与其他患者相比，品行障碍患者更年轻且受教育程度更低。药物使用、注射吸毒和海洛因使用的起始时间平均比其他患者早2年，且他们有更广泛的注射多种药物使用史。品行障碍患者更有可能自杀未遂且在未遂后住院，以及在接受当前治疗期间自杀未遂。当前研究表明，品行障碍史会增加自杀未遂风险，这种风险超过了注射吸毒本身所带来的更高风险。
