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获得性泪溢与慢性鼻-鼻窦炎的体征和症状之间的关联:一项前瞻性病例对照研究。

An association between acquired epiphora and the signs and symptoms of chronic rhinosinusitis: a prospective case-control study.

作者信息

Annamalai Sivakumar, Kumar N Ajith, Madkour M B, Sivakumar Saraswati, Kubba Haytham

机构信息

Department of Otolaryngology, Ysbyty Gwyned, Bangor, Wales.

出版信息

Am J Rhinol. 2003 Mar-Apr;17(2):111-4.

Abstract

BACKGROUND

It has been suggested that chronic rhinosinusitis may lead to epiphora because of inflammatory edema at the nasal end of the nasolacrimal duct and that treatment of the underlying nasal disease may obviate the need for dacryocystorhinostomy. The aim of this study was to establish whether or not there is an association between the signs and symptoms of chronic rhinosinusitis and a complaint of epiphora in a blinded, prospective case-control study.

METHODS

A consecutive series of 15 adult patients presenting to the ophthalmology department with acquired epiphora were compared with 29 patients presenting with chronic open-angle glaucoma over the same study period. Nasal symptoms and the findings on nasal endoscopy were recorded by a single otolaryngologist blinded to the diagnosis and using a standardized staging system

RESULTS

The age and sex distributions of the two groups were similar. Scores for headache and altered smell were significantly higher in the epiphora cases than in controls (p = 0.05 and 0.03, respectively). Trends for higher scores for congestion and discharge were not statistically significant (p = 0.06 and 0.07, respectively). Mucosal edema and discharge were significantly more common on endoscopy in the epiphora cases than in the control cases (p < 0.02).

CONCLUSION

We have shown an association between rhinosinusitis and acquired epiphora, and this would be consistent with chronic rhinosinusitis being the cause of the epiphora in some cases.

摘要

背景

有人提出,慢性鼻-鼻窦炎可能由于鼻泪管鼻端的炎性水肿而导致溢泪,并且治疗潜在的鼻部疾病可能无需进行泪囊鼻腔吻合术。本研究的目的是在一项双盲、前瞻性病例对照研究中确定慢性鼻-鼻窦炎的体征和症状与溢泪主诉之间是否存在关联。

方法

在同一研究期间,将连续收治到眼科的15例成人获得性溢泪患者与29例慢性开角型青光眼患者进行比较。由一名对诊断不知情的耳鼻喉科医生使用标准化分期系统记录鼻部症状和鼻内镜检查结果。

结果

两组的年龄和性别分布相似。溢泪患者的头痛和嗅觉改变评分显著高于对照组(分别为p = 0.05和0.03)。充血和流涕评分较高的趋势无统计学意义(分别为p = 0.06和0.07)。鼻内镜检查显示,溢泪患者的黏膜水肿和流涕比对照组更常见(p < 0.02)。

结论

我们已经证明鼻-鼻窦炎与获得性溢泪之间存在关联,这与慢性鼻-鼻窦炎在某些情况下是溢泪的病因相符。

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