Papp Judit, Leiacker Richard, Keck Tilman, Rozsasi Ajnacska, Kappe Thomas
Department of PediatricOncology, University Children'sHospital, University of Ulm, Ulm, Germany.
Arch Otolaryngol Head Neck Surg. 2008 Sep;134(9):931-5. doi: 10.1001/archotol.134.9.931.
To compare nasal-air conditioning in patients with chronic rhinosinusitis with nasal polyposis with healthy control subjects without nasal pathologic conditions, to investigate nasal-air conditioning after endoscopic sinus surgery with and without septoplasty and turbinoplasty 4 to 6 weeks after surgery, to examine the parameters of nasal patency and nasal geometry that possibly influence nasal-air conditioning before and after endonasal surgery, and to determine their relationship to nasal-air conditioning parameters.
Prospective cohort study.
Tertiary referral center.
Twenty-five patients (median age, 51 years; age range, 20-74 years) having a diagnosis of chronic rhinosinusitis with nasal polyposis refractory to medical treatment and 22 healthy control subjects (median age, 25 years; age range, 18-52 years).
Patients underwent endoscopic sinus surgery with or without septoplasty and turbinoplasty during 6 months and were followed up 4 to 6 weeks after surgery.
Nasal-air conditioning was measured and acoustic rhinometry and active anterior rhinomanometry were performed before and after nasal surgery.
Nasal airflow and nasal volume were significantly higher postoperatively than preoperatively. The preoperative heat increase and water gradient were lower in the patients compared with the controls. The postoperative heat increase was significantly higher than the preoperative values. The water gradient did not change after endonasal surgery. Nasal patency and volume were positively correlated with nasal heating, whereas nasal humidification showed a significant negative correlation with nasal volume.
Patients with chronic rhinosinusitis with nasal polyposis seem to benefit from endoscopic sinus surgery with or without septoplasty and turbinoplasty because nasal heating is improved postoperatively. Four to 6 weeks after endonasal surgery, nasal humidification is neither improved nor worsened compared with preoperative values.
比较慢性鼻-鼻窦炎伴鼻息肉患者与无鼻腔病理状况的健康对照者的鼻腔空气调节功能；研究在接受或未接受鼻中隔成形术和鼻甲成形术的情况下，内镜鼻窦手术后4至6周的鼻腔空气调节功能；检查鼻内镜手术前后可能影响鼻腔空气调节功能的鼻腔通畅度和鼻腔几何形态参数，并确定它们与鼻腔空气调节参数的关系。
前瞻性队列研究。
三级转诊中心。
25例诊断为慢性鼻-鼻窦炎伴鼻息肉且药物治疗无效的患者（中位年龄51岁；年龄范围20 - 74岁）和22名健康对照者（中位年龄25岁；年龄范围18 - 52岁）。
患者在6个月内接受了内镜鼻窦手术，有或无鼻中隔成形术和鼻甲成形术，并在术后4至6周进行随访。
在鼻腔手术前后测量鼻腔空气调节功能，并进行鼻声反射和主动前鼻测压。
术后鼻腔气流和鼻腔容积显著高于术前。与对照组相比，患者术前的热量增加和水分梯度较低。术后热量增加显著高于术前值。鼻内镜手术后水分梯度未发生变化。鼻腔通畅度和容积与鼻腔加热呈正相关，而鼻腔加湿与鼻腔容积呈显著负相关。
慢性鼻-鼻窦炎伴鼻息肉患者似乎从有或无鼻中隔成形术和鼻甲成形术的内镜鼻窦手术中获益，因为术后鼻腔加热功能得到改善。鼻内镜手术后4至6周，与术前值相比，鼻腔加湿功能既未改善也未恶化。
