Cederlund K, Högberg S, Jorfeldt L, Larsen F, Norman M, Rasmussen E, Tylén U
Department of Physiology and Thoracic Radiology, Karolinska Hospital, Stockholm, Sweden.
Acta Radiol. 2003 May;44(3):246-51. doi: 10.1080/j.1600-0455.2003.00060.x.
The aim of this study was to evaluate whether lung perfusion scintigraphy (LPS) contributes to the preoperative classification of emphysema heterogeneity in patients undergoing LVRS (lung volume reduction surgery) compared to classification based only on computed tomography (CT).
Forty-five potential candidates for LVRS were examined with CT and LPS. The distribution of emphysema within the lungs was visually classified into three categories: markedly heterogeneous, intermediately heterogeneous, or homogeneous. The results of the two imaging techniques were compared to an objective, CT-based computerized classification of heterogeneity.
Visual evaluation of all 90 lungs resulted in 50 correct classifications based on CT, in 40 based on LPS and in 68 correct classifications based on the combination of CT and LPS. The combination was superior to CT alone (p<0.01) in classification of emphysema heterogeneity. There was no significant difference between the evaluations based on either CT or LPS.
The combined information from CT and LPS are superior in assessing emphysema heterogeneity prior to LVRS.
本研究的目的是评估与仅基于计算机断层扫描（CT）的分类相比，肺灌注闪烁扫描（LPS）是否有助于接受肺减容手术（LVRS）患者术前肺气肿异质性的分类。
对45名LVRS潜在候选者进行了CT和LPS检查。肺部肺气肿的分布在视觉上分为三类：明显异质性、中度异质性或均匀性。将这两种成像技术的结果与基于CT的客观计算机化异质性分类进行比较。
对所有90个肺进行视觉评估，基于CT有50个正确分类，基于LPS有40个正确分类，基于CT和LPS联合有68个正确分类。在肺气肿异质性分类方面，联合评估优于单独的CT（p<0.01）。基于CT或LPS的评估之间没有显著差异。
CT和LPS的联合信息在LVRS术前评估肺气肿异质性方面更具优势。
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