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局灶性下消化道出血超选择性经导管栓塞术后肠道的形态学和组织病理学变化

Morphologic and histopathologic changes in the bowel after super-selective transcatheter embolization for focal lower gastrointestinal hemorrhage.

作者信息

Horiguchi J, Naito A, Fukuda H, Nakashige A, Ito K, Kiso T, Mori M

机构信息

Department of Radiology, Division of Medical Intelligence and Informatics, Programs for Applied Biomedicine, Graduate School of Biomedical Sciences, Hiroshima University, Japan.

出版信息

Acta Radiol. 2003 May;44(3):334-9. doi: 10.1080/j.1600-0455.2003.00062.x.

DOI:10.1080/j.1600-0455.2003.00062.x
PMID:12752008
Abstract

PURPOSE

To evaluate the safety of superselective arterial embolization therapy in the lower gastrointestinal tract. The sequelae on normal enteric tissue in lower gastrointestinal arterial embolization were retrospectively reviewed.

MATERIAL AND METHODS

To control hemorrhage and tumor blood supply, 14 patients were treated by superselective transcatheter embolization at different levels of the colonic and small intestine vessels via the superior and inferior mesenteric arteries using microcoils and/or gelatin sponge. Normal enteric tissues in the embolized areas were analyzed for the occurrence of ischemic changes by clinical follow-up, colonoscopy, and surgery.

RESULTS

Normal bowel function was preserved in 13 patients. In 1 patient treated with numerous gelatin sponge particles delivered from the proximal arcade of the superior mesenteric artery, significant muscular fibrosis occurred.

CONCLUSION

Superselective arterial embolization for lower gastrointestinal hemorrhage can be safely performed by minimizing the amount of embolic materials and delivering them as distally as possible.

摘要

目的

评估超选择性动脉栓塞治疗在下消化道的安全性。回顾性分析下消化道动脉栓塞对正常肠组织的后遗症。

材料与方法

为控制出血和肿瘤血供,14例患者通过经导管超选择性栓塞,经肠系膜上动脉和肠系膜下动脉在结肠和小肠血管的不同水平使用微线圈和/或明胶海绵进行治疗。通过临床随访、结肠镜检查和手术分析栓塞区域正常肠组织缺血改变的发生情况。

结果

13例患者肠道功能正常。1例经肠系膜上动脉近端弓注入大量明胶海绵颗粒治疗的患者出现明显的肌肉纤维化。

结论

通过尽量减少栓塞材料的用量并尽可能向远端输送,可以安全地进行下消化道出血的超选择性动脉栓塞。

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