Berg J N, Brown L N, Ennis P G, Self H L
Am J Vet Res. 1976 May;37(5):509-12.
Foot rot was experimentally induced in feedlot cattle with a mixed inoculum of Fusobacterium necrophorum (Sphaerophorus necrophus) and Bacteroides melaninogenicus. Both bacteria were isolated from the lesions. Isolates of F necrophorum from 2 of the lesions were serologically compared, using a passive hemagglutination test with the strain used to induce the lesions. These isolates were serologically similar but not identical, indicating antigenic change had occurred during animal passage. The addition of ethylenediamine dihydriodide or urea to the rations did not affect the frequency of experimentally induced foot rot.
用坏死梭杆菌（坏死梭形杆菌）和产黑素拟杆菌的混合接种物在饲养场的牛中实验性诱发腐蹄病。这两种细菌均从病变部位分离得到。使用用于诱发病变的菌株通过被动血凝试验对来自2个病变部位的坏死梭杆菌分离株进行血清学比较。这些分离株在血清学上相似但不相同，表明在动物传代过程中发生了抗原变化。在日粮中添加乙二胺二氢碘化物或尿素并不影响实验性诱发腐蹄病的频率。
