勿对（第二）信使“开火”：内膜转运体与结合蛋白调节胞质钙离子水平。

Don't shoot the (second) messenger: endomembrane transporters and binding proteins modulate cytosolic Ca2+ levels.

作者信息

Pittman Jon K, Hirschi Kendal D

机构信息

US Department of Agriculture/Agricultural Research Service Children's Nutrition Research Center, Baylor College of Medicine, 1100 Bates Street, Houston, Texas 77030, USA.

出版信息

Curr Opin Plant Biol. 2003 Jun;6(3):257-62. doi: 10.1016/s1369-5266(03)00036-0.

DOI:10.1016/s1369-5266(03)00036-0

PMID:12753975

Abstract

Ca(2+) signal transduction requires the meticulous regulation of cytosolic Ca(2+) levels. Endomembrane Ca(2+) transporters and binding proteins are important components in partitioning these Ca(2+) signals to mediate cellular activity. Recently, many of these proteins have been characterized and mutant analysis suggests that these transporters form a network. Future attempts to manipulate plant Ca(2+) signaling must address all aspects of this complex.

摘要

钙离子（Ca(2+)）信号转导需要对胞质钙离子水平进行精确调控。内膜钙离子转运蛋白和结合蛋白是将这些钙离子信号进行分配以介导细胞活动的重要组成部分。最近，许多这类蛋白已得到表征，突变分析表明这些转运蛋白构成一个网络。未来操纵植物钙离子信号的尝试必须应对这一复杂体系的所有方面。