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终板生物力学特性在颈椎前路融合术中的作用。

Role of the biomechanical property of the endplate in anterior cervical fusion.

作者信息

Li Jian-yi, Zhu Qing-an, Yuan Lin, Zhao Wei-dong, Lin Li-jun, Zhang Mei-chao, Huang Wen-hua

机构信息

Key Laboratory of Medical Biomechanics of PLA, First Military Medical University, Guangzhou 510515, China.

出版信息

Di Yi Jun Yi Da Xue Xue Bao. 2003 May;23(5):402-8.

PMID:12754113
Abstract

OBJECTIVE

To study the distribution of the biomechanical properties in the cervical vertebrae with or without the endplate, so as to evaluate the importance of the endplate in cervical anterior fusion.

METHODS

Indentation tests were performed at 20 standardized testing points chosen on each surface of the endplate with the impact adjusted perpendicular to the endplate surface using a hemispherical indenter 2 mm in diameter. The failure load and rigidity at each test site were determined from the load-displacement curves. Independent sample t test and factorial analyses were used to analyze the results.

RESULTS

On either superior or inferior endplate surface, both the failure load and rigidity differed significantly between the endplate-intact and endplate-removed groups (P < 0.001). The posterior region of the superior endplate and the lateral regions of the inferior endplate were stronger and more rigid than any other region across the endplate surface in the endplate-intact group, while for enplate-removed group, the posterior region of the superior endplate and the posterolateral regions of the inferior endplate were the stronger and more rigid.

CONCLUSION

The endplate plays an important role in deciding the success of anterior cervical fusion, and due attention should be paid to the endplate in the intervertebral implant device designing and the surgical approach modification.

摘要

目的

研究有无终板的颈椎生物力学特性分布,以评估终板在颈椎前路融合中的重要性。

方法

使用直径2mm的半球形压头,在终板每个表面上选择的20个标准化测试点进行压痕试验,使冲击垂直于终板表面进行调整。根据载荷-位移曲线确定每个测试部位的破坏载荷和刚度。采用独立样本t检验和析因分析对结果进行分析。

结果

在上终板或下终板表面,完整终板组和去除终板组的破坏载荷和刚度均有显著差异(P<0.001)。在完整终板组中,上终板的后部区域和下终板的外侧区域比终板表面的任何其他区域更强、更硬,而对于去除终板组,上终板的后部区域和下终板的后外侧区域更强、更硬。

结论

终板在决定颈椎前路融合的成功方面起着重要作用,在椎间植入装置设计和手术入路改良中应充分重视终板。

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Role of the biomechanical property of the endplate in anterior cervical fusion.终板生物力学特性在颈椎前路融合术中的作用。
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引用本文的文献

1
The distribution of mineral density in the cervical vertebral endplates.颈椎终板中矿物质密度的分布。
Eur Spine J. 2008 Mar;17(3):432-438. doi: 10.1007/s00586-008-0601-5. Epub 2008 Jan 12.
2
Correlation of cervical endplate strength with CT measured subchondral bone density.颈椎终板强度与CT测量的软骨下骨密度的相关性。
Eur Spine J. 2007 Dec;16(12):2104-9. doi: 10.1007/s00586-007-0482-z. Epub 2007 Aug 22.