[链霉肌动菌中链霉胍生物合成受阻的突变体]
[Actinomyces streptomycini mutant blocked in streptidine biosynthesis].
作者信息
Anisova L N, Kovalenko I V, Kornitskaia E I, Krasil'nikova O L, Soĭfer V S
出版信息
Antibiotiki. 1976 Jan;21(1):6-10.
PMID:1275456
Abstract
Mutant 170 not capable of forming streptidine and streptomycin was obtained using chemical mutagenes. This mutant can produce streptomycin only with suplementation of exogenous streptidine. Experiment with labeled C14-streptidine showed its specific incorporation in streptidine moiety of streptomycin molecule.
摘要
利用化学诱变剂获得了无法合成链霉胍和链霉素的突变体170。该突变体只有在补充外源链霉胍的情况下才能产生链霉素。用标记的C14-链霉胍进行的实验表明，它能特异性地掺入链霉素分子的链霉胍部分。
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