Murzina G B
Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Moscow.
Zh Vyssh Nerv Deiat Im I P Pavlova. 2003 Mar-Apr;53(2):184-90.
Mechanisms of associative and homosynaptic long-term depression (LTD) in cerebellar Purkinje cells are discussed. The possibility of LTD induction related to a decrease in efficacy of AMPA receptors through either their dephosphorylation or phosphorylation is investigated by mathematical simulation.
本文讨论了小脑浦肯野细胞中联合性和同突触性长时程抑制(LTD)的机制。通过数学模拟研究了与AMPA受体效能降低相关的LTD诱导可能性,这种降低是通过其去磷酸化或磷酸化实现的。