Mitchell John D
Section of General Thoracic Surgery, Division of Cardiothoracic Surgery, University of Colorado School of Medicine, 4200 E. Ninth Avenue, C-310, Denver CO 80262, USA.
Chest Surg Clin N Am. 2003 May;13(2):315-29. doi: 10.1016/s1052-3359(03)00035-8.
Successful outcomes for carinal resection and reconstruction depend upon many factors. Careful patient selection for patients who can tolerate the physiologic effects of the operation cannot be underestimated. Understanding the safe limits of resection, the technical details of airway reconstruction, and ongoing improvements in intraoperative and postoperative care should minimize the morbidity and mortality rates previously reported with this procedure. In addition, further work from institutions with considerable experience in carinal resection is needed to better define the long-term outcome for patients with bronchogenic carcinoma in close proximity to or involving the carina. Prior studies have suggested reasonable survival rates can be expected in the absence of involved mediastinal nodes or distant metastatic disease.
隆突切除重建手术的成功结果取决于多种因素。对于能够耐受手术生理影响的患者进行仔细筛选,这一点不容小觑。了解切除的安全限度、气道重建的技术细节以及术中和术后护理的不断改进,应能将此前该手术报道的发病率和死亡率降至最低。此外,需要有丰富隆突切除经验的机构开展进一步研究,以更好地明确靠近或累及隆突的支气管源性癌患者的长期预后。先前的研究表明,在没有纵隔淋巴结受累或远处转移疾病的情况下,可以预期有合理的生存率。