Mathisen D J, Grillo H C
Department of Thoracic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston.
J Thorac Cardiovasc Surg. 1991 Jul;102(1):16-22; discussion 22-3.
Techniques are available for carinal resection and reconstruction for bronchogenic carcinoma involving the carina. Successful outcome depends on careful patient selection, thorough preoperative evaluation, careful anesthetic management, strict attention to surgical technique, and compulsive postoperative care. Since 1973 we have performed 37 carinal resections for bronchogenic carcinoma: 21 right carinal pneumonectomies, 7 carinal resections, 7 carina plus lobe resections, and 2 carina plus pneumonectomy stump resections. Five patients had diseased N2 nodes and 13 patients had diseased N1 nodes. Complications included pulmonary (8), vocal cord paresis (3), atrial fibrillation (9), anastomotic stenosis (4), and anastomotic separation (3). There were 3 early postoperative deaths (8%). All were related to adult respiratory distress syndrome and were unresponsive to aggressive treatment. There were 4 late postoperative deaths between 2 and 4 months (10.9%). All late postoperative deaths were related to anastomotic complications (stenosis [1] and separation [3]). There are 5 absolute 5-year survivors and an actuarial 5-year survival rate of 19%.
对于累及隆突的支气管源性癌,已有隆突切除及重建技术。成功的结果取决于仔细的患者选择、全面的术前评估、精心的麻醉管理、对手术技术的严格关注以及强制性的术后护理。自1973年以来,我们已对支气管源性癌进行了37例隆突切除术:21例右隆突全肺切除术、7例隆突切除术、7例隆突加肺叶切除术以及2例隆突加肺切除残端切除术。5例患者有N2淋巴结病变,13例患者有N1淋巴结病变。并发症包括肺部并发症(8例)、声带麻痹(3例)、心房颤动(9例)、吻合口狭窄(4例)以及吻合口裂开(3例)。术后早期死亡3例(8%)。均与成人呼吸窘迫综合征相关,积极治疗无效。术后晚期死亡4例,发生在术后2至4个月(10.9%)。所有术后晚期死亡均与吻合口并发症(狭窄[1例]和裂开[3例])相关。有5例绝对5年生存者,精算5年生存率为19%。