Doherty G M, Thompson N W
Department of Surgery, University of Michigan, Ann Arbor, MI 48109, USA.
J Intern Med. 2003 Jun;253(6):590-8. doi: 10.1046/j.1365-2796.2003.01163.x.
The pancreaticoduodenal disease in Multiple endocrine neoplasia type 1 (MEN1) is the most frequent cause of death due to the syndrome, and the most controversial with regard to its management. This article discusses the current data and recommendations with respect to disease screening, functional tumour diagnosis, natural history, preoperative imaging, operative strategy and follow-up.
1型多发性内分泌腺瘤病(MEN1)中的胰十二指肠疾病是该综合征最常见的死亡原因,也是其治疗方面最具争议的问题。本文讨论了关于疾病筛查、功能性肿瘤诊断、自然病史、术前影像学检查、手术策略和随访的当前数据及建议。