豚鼠母体和胎儿组织在体内的脂质合成。
Lipid synthesis in vivo by tissues of the maternal and foetal guinea pig.
作者信息
Jones C T, Firmin W
出版信息
Biochem J. 1976 Jan 15;154(1):159-61. doi: 10.1042/bj1540159.
Abstract
The rate of lipid biosynthesis in vivo was determined in pregnant guinea pigs after maternal and foetal injections of 3H2O. Synthesis in the maternal tissues was low and in the foetal liver and adipose tissues relatively high. In the foetal liver it reached a peak at about two-thirds of gestation, whereas that in the foetal adipose tissue occurred later. These results were used to support the view that lipid synthesis in the foetal guinea-pig liver at two-thirds of gestation is largely from short-chain fatty acids, whereas in foetal adipose tissue glucose is probably the major substrate.
摘要
在给怀孕的豚鼠母体和胎儿注射3H2O后，测定了其体内脂质生物合成的速率。母体组织中的合成速率较低，而胎儿肝脏和脂肪组织中的合成速率相对较高。胎儿肝脏中的合成速率在妊娠约三分之二时达到峰值，而胎儿脂肪组织中的合成速率出现得较晚。这些结果被用来支持以下观点：妊娠三分之二时，胎儿豚鼠肝脏中的脂质合成主要来自短链脂肪酸，而胎儿脂肪组织中的主要底物可能是葡萄糖。
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