Vega-Franco L, González Díaz A M, Bello A
Bol Med Hosp Infant Mex. 1976 May-Jun;33(3):521-32.
With the purpose of analyzing the evolution in weight before and after treatment of megaloblastic anemia with folic acid, we studied the clinical changes and the evolution in weight in 8 malnourished children who developed this type of anemia during their recovery. Seven out of the 8 cases were less than 20 months of age; 5 of them came from mothers who had had five or more pregnancies; in 7 a history of diarrhea of prolonged course was presented and 2 cases had been given sodium diphenylhydantoin. Increase in weight before treatment of anemia with folic acid was lesser than the one for the days following treatment in seven of the patients. Simultaneously, an important change in behavior was appreciated, without being possible to atribute this change or the increase in weight to a quantitative change favorable to the ingestion of proteins and calories.
为了分析巨幼细胞贫血患儿用叶酸治疗前后体重的变化，我们研究了8名营养不良儿童在恢复过程中发生这种贫血时的临床变化和体重变化。8例中有7例年龄小于20个月；其中5例母亲有过5次或更多次妊娠；7例有长期腹泻史，2例曾服用苯妥英钠。7例患者在用叶酸治疗贫血前体重增加低于治疗后几天的体重增加。同时，观察到行为有重要变化，但无法将这种变化或体重增加归因于有利于蛋白质和热量摄入的定量变化。
