Chew P C, Ratnam S S, Salmon J A
Br J Obstet Gynaecol. 1976 Jun;83(6):430-3. doi: 10.1111/j.1471-0528.1976.tb00859.x.
Serial plasma oestriol levels were measured by a radioimmunoassay in 49 normal pregnancies, Plasma oestriol rose from 43 ng/ml (149-1 nmol/l) at 22 weeks to 357 ng/ml (1237-91 nmol/l) at 40 weeks. The rise was gradual between 22 and 32 weeks and steep between 32 and 40 weeks. No significant relationship could be found between plasma oestriol and parity, maternal age, maternal height, maternal weight or fetal sex. However, a significant but low correlation was found between birth weight and plasma oestriol prior to labour and also oestriol increments from 30 weeks to delivery. The average day to day coefficient of variation of plasma oestriol in 11 patients was found to be 16-2 per cent.
采用放射免疫分析法对49例正常妊娠孕妇进行了系列血浆雌三醇水平测定。血浆雌三醇水平在22周时为43 ng/ml（149 - 1 nmol/l），到40周时升至357 ng/ml（1237 - 91 nmol/l）。在22至32周之间上升较为平缓，而在32至40周之间则急剧上升。未发现血浆雌三醇与产次、产妇年龄、产妇身高、产妇体重或胎儿性别之间存在显著关系。然而，发现分娩前出生体重与血浆雌三醇之间存在显著但较低的相关性，以及从30周直至分娩时雌三醇的增量之间也存在显著但较低的相关性。11例患者血浆雌三醇的每日平均变异系数为16 - 2%。
