• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

室管膜瘤

Ependymoma.

作者信息

Teo Charles, Nakaji Peter, Symons Patricia, Tobias Vivienne, Cohn Richard, Smee Robert

机构信息

Department of Neurosurgery, Sydney Children's Hospital, Randwick, NSW 2031, Australia.

出版信息

Childs Nerv Syst. 2003 Jun;19(5-6):270-85. doi: 10.1007/s00381-003-0753-x. Epub 2003 May 22.

DOI:10.1007/s00381-003-0753-x
PMID:12761644
Abstract

INTRODUCTION

The management of a patient with an ependymoma is controversial. Although the necessity for a multi-disciplined approach is accepted, the exact roles for all disciplines are poorly defined.

REVIEW

This review article examines the current status of histopathological and cytogenetic diagnosis, surgical, chemotherapeutic and radiotherapeutic treatment and future directions.

摘要

引言

室管膜瘤患者的管理存在争议。尽管多学科方法的必要性已得到认可，但所有学科的确切作用仍定义不清。

综述

本文综述探讨了组织病理学和细胞遗传学诊断、手术、化疗和放疗治疗的现状以及未来方向。

相似文献

1
Ependymoma.室管膜瘤
Childs Nerv Syst. 2003 Jun;19(5-6):270-85. doi: 10.1007/s00381-003-0753-x. Epub 2003 May 22.
2
[Brain ependymoma].[脑室内神经胶质瘤]
Nihon Rinsho. 2005 Sep;63 Suppl 9:116-21.
3
Intramedullary spinal cord tumors: molecular insights and surgical innovation.脊髓髓内肿瘤：分子见解与手术创新
Clin Neurosurg. 2005;52:76-84.
4
Intracranial ependymomas of childhood: current management strategies.儿童颅内室管膜瘤：当前的治疗策略
Pediatr Neurosurg. 2000 Sep;33(3):138-50. doi: 10.1159/000028995.
5
Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma.明确两种具有临床和分子特征的后颅窝室管膜瘤亚群。
Cancer Cell. 2011 Aug 16;20(2):143-57. doi: 10.1016/j.ccr.2011.07.007.
6
Brain tumours: classification and genes.脑肿瘤：分类与基因
J Neurol Neurosurg Psychiatry. 2004 Jun;75 Suppl 2(Suppl 2):ii2-11. doi: 10.1136/jnnp.2004.040337.
7
[Intracranial, intrarachindial ependymomas. V. Ependymomas of the posterior cerebral fossa].[颅内、蛛网膜下腔室管膜瘤。V. 后颅窝室管膜瘤]
Neurochirurgie. 1977 May;23 Suppl 1:111-47.
8
Treatment implications of posterior fossa ependymoma subgroups.后颅窝室管膜瘤亚组的治疗意义
Chin J Cancer. 2016 Nov 15;35(1):93. doi: 10.1186/s40880-016-0155-6.
9
Pure cortical supratentorial extraventricular ependymoma.纯皮质幕上脑室外室管膜瘤
Neurol India. 2009 Mar-Apr;57(2):213-5. doi: 10.4103/0028-3886.51301.
10
The current consensus on the clinical management of intracranial ependymoma and its distinct molecular variants.颅内室管膜瘤及其不同分子变体临床管理的当前共识。
Acta Neuropathol. 2017 Jan;133(1):5-12. doi: 10.1007/s00401-016-1643-0. Epub 2016 Nov 17.

引用本文的文献

1
Intracytoplasmic dot-like inclusions as cytopathologically useful findings of ependymoma: Case report of adolescent supratentorial anaplastic ependymoma with clear cell morphology.作为室管膜瘤细胞病理学有用发现的胞浆内点状包涵体：青少年幕上间变性室管膜瘤伴透明细胞形态的病例报告。
Clin Case Rep. 2020 Nov 16;9(1):380-385. doi: 10.1002/ccr3.3536. eCollection 2021 Jan.
2
Cerebellopontine angle ependymoma in a young adult: A case report.一名年轻成年人的桥小脑角室管膜瘤：病例报告
Medicine (Baltimore). 2019 Apr;98(14):e15019. doi: 10.1097/MD.0000000000015019.
3
Prognostic Implications of Histological Clear Cells in High-Grade Intracranial Ependymal Tumors: A Retrospective Analysis from a Tertiary Care Hospital in Pakistan.

本文引用的文献

1
Ependymomas and choroid plexus papillomas.室管膜瘤和脉络丛乳头状瘤。
J Neuropathol Exp Neurol. 1949 Oct;8(4):355-80, illust. doi: 10.1097/00005072-194910000-00001.
2
Gain of 1q and loss of 22 are the most common changes detected by comparative genomic hybridisation in paediatric ependymoma.1q染色体获得和22号染色体缺失是小儿室管膜瘤中通过比较基因组杂交检测到的最常见变化。
Genes Chromosomes Cancer. 2001 Sep;32(1):59-66. doi: 10.1002/gcc.1167.
3
Identification of novel regions of allelic loss in ependymomas by high-resolution allelotyping with 384 microsatellite markers.
高级别颅内室管膜瘤中组织学透明细胞的预后意义：来自巴基斯坦一家三级护理医院的回顾性分析
Asian J Neurosurg. 2018 Apr-Jun;13(2):307-313. doi: 10.4103/ajns.AJNS_280_16.
4
Cerebellar ependymoma with overlapping features of clear-cell and tanycytic variants mimicking hemangioblastoma: a case report and literature review.具有透明细胞和室管膜细胞变体重叠特征且酷似血管母细胞瘤的小脑室管膜瘤：一例报告及文献综述
Diagn Pathol. 2017 Mar 20;12(1):28. doi: 10.1186/s13000-017-0619-2.
5
The Similarities and Differences between Intracranial and Spinal Ependymomas : A Review from a Genetic Research Perspective.颅内和脊髓室管膜瘤的异同：基于遗传学研究视角的综述
J Korean Neurosurg Soc. 2016 Mar;59(2):83-90. doi: 10.3340/jkns.2016.59.2.83. Epub 2016 Feb 29.
6
Ependymal tumors with oligodendroglioma like clear cells: Experience from a tertiary care hospital in Pakistan.具有少突胶质细胞瘤样透明细胞的室管膜瘤：来自巴基斯坦一家三级医疗医院的经验。
Surg Neurol Int. 2015 Nov 16;6(Suppl 23):S583-9. doi: 10.4103/2152-7806.169545. eCollection 2015.
7
One-year outcome of postoperative swallowing impairment in pediatric patients with posterior fossa brain tumor.小儿后颅窝脑肿瘤患者术后吞咽障碍的一年期转归
J Neurooncol. 2016 Mar;127(1):73-81. doi: 10.1007/s11060-015-2010-z. Epub 2015 Nov 30.
8
Clinical features and long-term outcomes of intraspinal ependymomas in pediatric patients.小儿脊髓内室管膜瘤的临床特征及长期预后
Childs Nerv Syst. 2014 Dec;30(12):2073-81. doi: 10.1007/s00381-014-2528-y. Epub 2014 Aug 21.
9
Supratentorial extraventricular anaplastic ependymoma in a child.一名儿童的幕上脑室外间变性室管膜瘤
BMJ Case Rep. 2014 Mar 12;2014:bcr2014203750. doi: 10.1136/bcr-2014-203750.
10
Ependymoma stem cells are highly sensitive to temozolomide in vitro and in orthotopic models.室管膜瘤干细胞在体外和原位模型中对替莫唑胺高度敏感。
Neuro Oncol. 2014 Aug;16(8):1067-77. doi: 10.1093/neuonc/nou008. Epub 2014 Feb 12.
通过使用384个微卫星标记进行高分辨率等位基因分型鉴定室管膜瘤中新型等位基因缺失区域。
J Neurosurg. 2001 Jul;95(1):9-14. doi: 10.3171/jns.2001.95.1.0009.
4
Supratentorial ependymoma in children.儿童幕上室管膜瘤
Pediatr Neurosurg. 2001 Feb;34(2):77-87. doi: 10.1159/000055999.
5
Molecular genetic alterations on chromosomes 11 and 22 in ependymomas.室管膜瘤中11号和22号染色体的分子遗传学改变。
Int J Cancer. 2001 Mar 15;91(6):803-8. doi: 10.1002/1097-0215(200002)9999:9999<::aid-ijc1134>3.0.co;2-p.
6
Chromosomal abnormalities subdivide ependymal tumors into clinically relevant groups.染色体异常将室管膜瘤细分为具有临床相关性的组。
Am J Pathol. 2001 Mar;158(3):1137-43. doi: 10.1016/S0002-9440(10)64061-8.
7
Postoperative chemotherapy without irradiation for ependymoma in children under 5 years of age: a multicenter trial of the French Society of Pediatric Oncology.5岁以下儿童室管膜瘤术后不进行放疗的化疗：法国儿科肿瘤学会的一项多中心试验
J Clin Oncol. 2001 Mar 1;19(5):1288-96. doi: 10.1200/JCO.2001.19.5.1288.
8
Supratentorial giant cell ependymoma.幕上巨细胞型室管膜瘤
Clin Neuropathol. 2001 Jan-Feb;20(1):31-7.
9
Bone metastases from a cerebral and sacral ependymoma. Report of a case.脑和骶骨室管膜瘤的骨转移。病例报告。
Joint Bone Spine. 2000;67(5):471-4.
10
Intracranial ependymomas of childhood: current management strategies.儿童颅内室管膜瘤：当前的治疗策略
Pediatr Neurosurg. 2000 Sep;33(3):138-50. doi: 10.1159/000028995.