Kalkanis Steven N, Eskandar Emad N, Carter Bob S, Barker Fred G
Neurosurgical Service, Massachusetts General Hospital, 32 Fruit Street, Boston, MA 02114, USA.
Neurosurgery. 2003 Jun;52(6):1251-61; discussion 1261-2. doi: 10.1227/01.neu.0000065129.25359.ee.
Microvascular decompression (MVD) is associated with low mortality and morbidity rates at specialized centers, but many MVD procedures are performed outside such centers. We studied short-term end points after MVD in a national hospital discharge database sample.
A retrospective cohort study was performed by using the Nationwide Inpatient Sample, 1996 to 2000.
The sample included 1326 MVD procedures for treatment of trigeminal neuralgia, 237 for treatment of hemifacial spasm, and 27 for treatment of glossopharyngeal neuralgia, performed at 305 hospitals by 277 identified surgeons. The mortality rate was 0.3%, and the rate of discharge other than to home was 3.8%. Neurological complications were coded in 1.7% of cases, hematomas in 0.5%, and facial palsies in 0.6%, with 0.4% of patients requiring ventriculostomies and 0.7% postoperative ventilation. Trigeminal nerve section was also coded for 3.4% of patients with trigeminal neuralgia, more commonly among older patients (P = 0.08), among female patients (P = 0.03), and at teaching hospitals (P = 0.02). The median annual caseloads were 5 cases per hospital (range, 1-195 cases) and 3 cases per surgeon (range, 1-107 cases). With adjustment for age, sex, race, primary insurance, diagnosis (trigeminal neuralgia versus hemifacial spasm versus glossopharyngeal neuralgia), geographic region, admission type and source, and medical comorbidities, outcomes at discharge were superior at higher-volume hospitals (P = 0.006) and with higher-volume surgeons (P = 0.02). Complications were less frequent after surgery performed at high-volume hospitals (P = 0.04) or by high-volume surgeons (P = 0.01). The rate of discharge other than to home was 5.1% for the lowest-volume-quartile hospitals, compared with 1.6% for the highest-volume-quartile hospitals. Volume and mortality rate were not significantly related, but three of the four deaths in the series followed procedures performed by surgeons who had performed only one MVD procedure that year. Length of stay (median, 3 d) and hospital volume were not significantly related. Hospital charges were slightly higher at higher-volume hospitals (P = 0.007).
Although most MVD procedures in the United States are performed at low-volume centers, mortality rates remain low. Morbidity rates are significantly lower at high-volume hospitals and with high-volume surgeons.
在专业中心,微血管减压术(MVD)的死亡率和发病率较低,但许多MVD手术是在这些中心以外进行的。我们在一个国家医院出院数据库样本中研究了MVD后的短期终点。
利用1996年至2000年的全国住院患者样本进行回顾性队列研究。
该样本包括在305家医院由277名已确认的外科医生进行的1326例用于治疗三叉神经痛的MVD手术、237例用于治疗面肌痉挛的手术以及27例用于治疗舌咽神经痛的手术。死亡率为0.3%,非回家出院率为3.8%。1.7%的病例记录有神经并发症,0.5%有血肿,0.6%有面瘫,0.4%的患者需要进行脑室造瘘术,0.7%的患者术后需要通气。3.4%的三叉神经痛患者记录有三叉神经切断术,在老年患者(P = 0.08)、女性患者(P = 0.03)和教学医院(P = 0.02)中更为常见。每家医院的年病例数中位数为5例(范围为1 - 195例),每位外科医生的年病例数中位数为3例(范围为1 - 107例)。在对年龄、性别、种族、主要保险、诊断(三叉神经痛与面肌痉挛与舌咽神经痛)、地理区域、入院类型和来源以及合并症进行调整后,高容量医院出院时的结局更好(P = 0.006),高容量外科医生的结局也更好(P = 0.02)。在高容量医院进行的手术(P = 0.04)或由高容量外科医生进行的手术(P = 0.01)后并发症较少。病例数最低四分位数的医院非回家出院率为5.1%,而病例数最高四分位数的医院为1.6%。手术量与死亡率无显著相关性,但该系列中的4例死亡中有3例是由当年仅进行了1例MVD手术的外科医生实施手术后发生的。住院时间(中位数为3天)与医院手术量无显著相关性。高容量医院的住院费用略高(P = 0.007)。
尽管美国大多数MVD手术是在低容量中心进行的,但死亡率仍然较低。高容量医院和高容量外科医生的发病率显著较低。