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[迟发型超敏反应期间免疫淋巴细胞对自体系统淋巴结“黏附”细胞(巨噬细胞)的细胞毒性作用]

[Cytotoxic action of immune lymphocytes on "adherent" cells (macrophages) of autologous system lymph nodes during delayed hypersensitivity].

作者信息

Smirnova M N, Bazanova E A, Liampert I M

出版信息

Biull Eksp Biol Med. 1976;81(4):465-7.

PMID:1276451
Abstract

A study was made in the autologous system of the cytotoxic action of immune lymphocytes on the "adherent" cells (macrophages) of the lymph nodes of guinea pigs in delayed hypersensitivity (DH) to the streptococcus antigens and tuberculoproteins. Death of a considerable number of the "adherent" cells in cultivation of a suspension of cells of the lymph nodes of animals sensitized with the culture of streptococcus or BCG in the presence of specific antigen (thermo-stable streptococcus fraction or tuberculin, respectively) alone. Detection of death of the "adherent" cells in the autologous system can be used as one of specific and sensitive tests in studying the DH.

摘要

对豚鼠淋巴结“黏附”细胞(巨噬细胞)在对链球菌抗原和结核蛋白的迟发型超敏反应(DH)中免疫淋巴细胞的细胞毒性作用进行了自体系统研究。在用链球菌培养物或卡介苗致敏的动物的淋巴结细胞悬液单独在存在特异性抗原(分别为热稳定链球菌组分或结核菌素)的情况下培养时,相当数量的“黏附”细胞死亡。在自体系统中检测“黏附”细胞的死亡可作为研究DH的特异性和敏感试验之一。

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