Asmussen Helle, Jørgensen Lise
Anaestesi- og Operationsafdelingen, HovedOrtoCentret, H:S Rigshospitalet, DK-2100 København ø.
Ugeskr Laeger. 2003 Apr 21;165(17):1774-8.
The aim of this study was to investigate how many patients, after anesthesia with either propofol/remifentanil or propofol/fentanyl/alfentanil, within 20 minutes from the end of surgery could be transferred directly to the general ward. The number of undesired preoperative incidents, the anesthetists', the surgeons', and the patients' evaluations of the anesthesia were registered. An evaluation of the economic consequences of the two methods was also intended.
The study was clinically controlled, randomised, and partly blinded. A total of 80 patients undergoing eye surgery were recruited. The patients were scored 10, 15, and 20 minutes after the end of surgery according to a modified Aldrete score. With sufficient awakening score, the patients were transferred to the general ward.
Thirty-six patients in each group underwent the examination. In the propofol/remifentanil-group 31 (86%) could be transferred to the general ward compared to 15 (42%) in the proponol/fentanyl/alfentanil-group. In the propofol/remifentanil-group there were less reactions to the start of surgery, more episodes with preoperative hypotension and postoperative shivering. Otherwise there were no differences between the groups. It was estimated that the additional expenses for medcine were by far outweighed by the lower costs postoperatively.
With a propofol/remifentanil-anesthesia, the patients had a predictably short awakening time, so they could be transferred directly to the general ward. This may, especially in ambulatory surgery, mean cost savings and perhaps higher patient satisfaction.
本研究的目的是调查在手术结束后20分钟内,使用丙泊酚/瑞芬太尼或丙泊酚/芬太尼/阿芬太尼麻醉的患者中有多少可以直接转入普通病房。记录术前不良事件的数量、麻醉医生、外科医生和患者对麻醉的评价。还打算对两种方法的经济后果进行评估。
本研究为临床对照、随机且部分盲法研究。共招募了80例接受眼科手术的患者。术后10、15和20分钟根据改良的Aldrete评分对患者进行评分。当苏醒评分足够时,患者被转入普通病房。
每组36例患者接受检查。丙泊酚/瑞芬太尼组有31例(86%)可转入普通病房,而丙泊酚/芬太尼/阿芬太尼组为15例(42%)。丙泊酚/瑞芬太尼组对手术开始的反应较少,术前低血压和术后寒战的发作较多。除此之外,两组之间没有差异。据估计,药物的额外费用远远被术后较低的成本所抵消。
使用丙泊酚/瑞芬太尼麻醉时,患者的苏醒时间可预测地较短,因此他们可以直接转入普通病房。这在门诊手术中尤其如此,可能意味着成本节约,也许还能提高患者满意度。