Lentle B C, Jackson F I, Dierich H
Can Med Assoc J. 1976 Jun 19;114(12):1113-8.
Fifty consecutive patients in whom occult primary malignant disease was suspected underwent scintiscanning of the head, neck and trunk with gallium-67-citrate. In 17 patients a carcinoma was correctly identified as to presence and approximate location. In another seven patients the site of the primary tumour was identified from the scan and confirmed by radiologic study but no histopathological diagnosis, except for metastatic anaplastic carcinoma, was made. In another five patients the many abnormalities on the scan did not permit identification of a possible site of the primary tumour. Eleven patients had normal scintiscans and no evidence of malignant disease on follow-up. In seven patients with proven carcinoma false-negative results were obtained: no uptake of the radioisotope was detected, even at the sites of known disease. In three patients false-positive uptake of the radiotracer was observed; two had benign disease and one had a malignant tumour remote from the scan abnormality.
五十名疑似隐匿性原发性恶性疾病的连续患者接受了用枸橼酸镓-67对头、颈和躯干进行的闪烁扫描。在17名患者中，正确识别出了癌的存在及大致位置。在另外7名患者中，从扫描中确定了原发性肿瘤的部位，并经放射学检查证实，但除转移性间变性癌外，未作出组织病理学诊断。在另外5名患者中，扫描上的许多异常情况无法确定原发性肿瘤的可能部位。11名患者闪烁扫描正常，随访中无恶性疾病证据。在7名已证实患有癌的患者中获得了假阴性结果：即使在已知疾病部位也未检测到放射性同位素摄取。在3名患者中观察到放射性示踪剂的假阳性摄取；2名患有良性疾病，1名患有远离扫描异常部位的恶性肿瘤。
