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常规更换带隧道、带 cuff 的血液透析导管可消除导管相关菌血症患者的椎旁/椎体感染。

Routine replacement of tunneled, cuffed, hemodialysis catheters eliminates paraspinal/vertebral infections in patients with catheter-associated bacteremia.

作者信息

Philipneri Marie, Al-Aly Ziyad, Amin Kamal, Gellens Mary E, Bastani Bahar

机构信息

Division of Nephrology, Saint Louis University Health Sciences Center, Saint Louis, MO 63110, USA.

出版信息

Am J Nephrol. 2003 Jul-Aug;23(4):202-7. doi: 10.1159/000071479. Epub 2003 May 27.

Abstract

BACKGROUND

Management of tunneled, cuffed, central venous catheters in hemodialysis (HD) patients with bacteremia remains a challenge. Attempts to salvage the catheter with systemic antibiotics alone have been associated with increased risk of metastatic infectious complications.

METHODS

Retrospective case series of patients with infectious complications in a chronic dialysis unit, affiliated with a tertiary care university hospital.

RESULTS

Between 1996 and 1999, when we treated HD catheter-associated bacteremia with systemic antibiotics alone, we encountered a clustering of 8 cases of paraspinal/vertebral infections in a population of 162 patients. After changing our protocol, i.e., routine catheter exchange over a guide wire at approximately 48 h, while on systemic antibiotic therapy, we did not encounter any new cases of paraspinal/vertebral infections over a 15-month period.

CONCLUSION

Our experience suggests that routine exchange of tunneled, cuffed catheters over a guide wire in HD patients presenting with bacteremia may significantly reduce serious infectious complications, e.g., epidural abscess/vertebral osteomyelitis.

摘要

背景

对于患有菌血症的血液透析(HD)患者,带隧道涤纶套中心静脉导管的管理仍然是一项挑战。仅使用全身抗生素挽救导管的尝试与转移性感染并发症风险增加有关。

方法

对一家隶属于三级护理大学医院的慢性透析单元中患有感染并发症的患者进行回顾性病例系列研究。

结果

1996年至1999年期间,当我们仅用全身抗生素治疗HD导管相关菌血症时,在162名患者中出现了8例椎旁/脊柱感染聚集病例。在改变我们的方案后,即在全身抗生素治疗期间,大约48小时经导丝进行常规导管更换,在15个月的时间里我们没有遇到任何新的椎旁/脊柱感染病例。

结论

我们的经验表明,对于出现菌血症的HD患者,经导丝对带隧道涤纶套导管进行常规更换可能会显著减少严重感染并发症,如硬膜外脓肿/脊椎骨髓炎。

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