Marghoob Ashfaq A, Borrego John Paul, Halpern Allan C
Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.
Semin Cutan Med Surg. 2003 Mar;22(1):21-32. doi: 10.1053/sder.2003.50002.
Congenital melanocytic nevi can be cosmetically disfiguring, give rise to melanoma, and suggest the presence of neurocutaneous melanocytosis. Management decisions must be tailored for each patient and each nevus, taking into consideration the risk for developing malignancy, risk for developing symptomatic neurocutaneous melanocytosis, cosmetic implications of having the nevus, cosmetic implications of any resultant surgical scars from their removal, adverse effects that the nevus may have on psycho-social development, and the adverse effects and long-term sequelae of any surgical intervention. The advantages and disadvantages of different modalities used in the treatment of congenital melanocytic nevi are discussed. Organizational flow diagrams are presented to help clinicians in managing patients with different sized congenital melanocytic nevi.
先天性黑素细胞痣可在外观上造成毁损,引发黑色素瘤,并提示存在神经皮肤黑素沉着症。管理决策必须针对每位患者和每颗痣进行量身定制,要考虑发生恶性病变的风险、出现有症状的神经皮肤黑素沉着症的风险、痣的外观影响、去除痣后任何手术疤痕的外观影响、痣可能对心理社会发育产生的不良影响,以及任何手术干预的不良影响和长期后遗症。本文讨论了用于治疗先天性黑素细胞痣的不同方式的优缺点。还提供了组织流程图,以帮助临床医生管理不同大小先天性黑素细胞痣的患者。