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“皮质震颤”的临床与电生理特征

[Clinical and electrophysiological features of "cortical tremor"].

作者信息

Delval A, Krystkowiak P, Cassim F, Szurhaj W, Charpentier P, Mastain B, Guieu J D, Destée A, Defebvre L

机构信息

Service de Neurologie et Pathologie du Mouvement, Clinique Neurologique, CHRU, Lille.

出版信息

Rev Neurol (Paris). 2003 May;159(5 Pt 1):518-27.

Abstract

The purpose of this paper is to draw attention to one particular variant of tremor named "cortical tremor," which corresponds to rhythmic cortical myoclonus whose principal differential diagnosis is essential tremor. Diagnosis may be established with electrophysiological explorations (electromyography, accelerometry, electroencelography with back averaging, long latency reflexes, giant somesthesic evoked potentials). Clinical and electrophysiological features of 15 patients are reported and compared to cases previously published. Association with generalized or partial seizures is possible. Other cases in the family are often mentioned with a dominant autosomal transmission. The therapeutic approach is based on the use of antiepileptic drugs.

摘要

本文的目的是提请注意一种名为“皮质震颤”的特殊震颤变体,它对应于节律性皮质肌阵挛,其主要鉴别诊断是特发性震颤。可通过电生理检查(肌电图、加速度测量、采用逆向平均的脑电图、长潜伏期反射、巨大体感诱发电位)来确诊。报告了15例患者的临床和电生理特征,并与先前发表的病例进行了比较。可能与全身性或部分性癫痫发作有关。家族中的其他病例常被提及,呈常染色体显性遗传。治疗方法基于使用抗癫痫药物。

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