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何时撤离呼吸机:基于证据的策略

When to wean from a ventilator: an evidence-based strategy.

作者信息

Frutos-Vivar Fernando, Esteban Andrés

机构信息

Intensive Care Unit, Hospital Universitario de Getafe, Madrid, Spain.

出版信息

Cleve Clin J Med. 2003 May;70(5):389, 392-3, 397 passim. doi: 10.3949/ccjm.70.5.389.

DOI:10.3949/ccjm.70.5.389
PMID:12779129
Abstract

It is often unclear when and how to wean patients from mechanical ventilation. We have devised an evidence-based protocol in which patients undergo a 30-minute trial of spontaneous breathing with a T tube or pressure support of 7 cm H2O. Those who can tolerate the trial are extubated, while those who cannot are reconnected to mechanical ventilation but undergo another trial every day until they can be extubated. More study is needed to improve the criteria to predict successful spontaneous breathing and extubation, and to clarify the role of non-invasive ventilation to avoid reintubation.

摘要

何时以及如何让患者脱离机械通气往往并不明确。我们制定了一项基于证据的方案,即让患者使用T形管或7厘米水柱的压力支持进行30分钟的自主呼吸试验。能够耐受该试验的患者进行拔管,而不能耐受的患者则重新连接机械通气,但每天进行另一次试验,直到能够拔管。需要更多的研究来改进预测自主呼吸和拔管成功的标准,并阐明无创通气在避免再次插管方面的作用。

相似文献

1
When to wean from a ventilator: an evidence-based strategy.何时撤离呼吸机:基于证据的策略
Cleve Clin J Med. 2003 May;70(5):389, 392-3, 397 passim. doi: 10.3949/ccjm.70.5.389.
2
Extubation outcome after spontaneous breathing trials with T-tube or pressure support ventilation. The Spanish Lung Failure Collaborative Group.使用T型管或压力支持通气进行自主呼吸试验后的拔管结果。西班牙肺衰竭协作组。
Am J Respir Crit Care Med. 1997 Aug;156(2 Pt 1):459-65. doi: 10.1164/ajrccm.156.2.9610109.
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Weaning from mechanical ventilation with pressure support in patients failing a T-tube trial of spontaneous breathing.在自主呼吸T型管试验失败的患者中采用压力支持撤机。
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Comparison of Proportional Assist Ventilation Plus, T-Tube Ventilation, and Pressure Support Ventilation as Spontaneous Breathing Trials for Extubation: A Randomized Study.比例辅助通气联合、T管通气和压力支持通气作为拔管自主呼吸试验的比较:一项随机研究
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Central venous saturation is a predictor of reintubation in difficult-to-wean patients.中心静脉血氧饱和度是预测撤机困难患者需要再次插管的指标。
Crit Care Med. 2010 Feb;38(2):491-6. doi: 10.1097/CCM.0b013e3181bc81ec.
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Comparison of pressure support and T-tube weaning from mechanical ventilation: randomized prospective study.机械通气撤机时压力支持与T型管撤机的比较:随机前瞻性研究
Croat Med J. 2004 Apr;45(2):162-6.
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Wean earlier and automatically with new technology (the WEAN study). A multicenter, pilot randomized controlled trial.采用新技术尽早自动断奶(WEAN 研究)。一项多中心、先导性随机对照试验。
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To Wean or Not to Wean: A Practical Patient Focused Guide to Ventilator Weaning.脱机还是继续机械通气:实用的以患者为中心的呼吸机脱机指南。
J Intensive Care Med. 2022 Nov;37(11):1417-1425. doi: 10.1177/08850666221095436. Epub 2022 Jul 11.

引用本文的文献

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Is non-thyroidal illness syndrome a predictor for prolonged weaning in intubated chronic obstructive pulmonary disease patients?非甲状腺疾病综合征是插管慢性阻塞性肺疾病患者长期撤机的预测指标吗?
Int J Clin Exp Med. 2015 Jun 15;8(6):10114-21. eCollection 2015.
2
Developing a readiness assessment tool for weaning patients under mechanical ventilation.开发一种用于机械通气患者撤机的准备情况评估工具。
Iran J Nurs Midwifery Res. 2014 May;19(3):273-8.
3
Short-term effects of positive expiratory airway pressure in patients being weaned from mechanical ventilation.
机械通气撤机患者应用呼气正压通气的短期效果。
Clinics (Sao Paulo). 2009 May;64(5):403-8. doi: 10.1590/s1807-59322009000500006.
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Prediction of extubation outcome: a randomised, controlled trial with automatic tube compensation vs. pressure support ventilation.预测拔管结果:自动管补偿与压力支持通气的随机对照试验。
Crit Care. 2009;13(1):R21. doi: 10.1186/cc7724. Epub 2009 Feb 23.