Cascio Brett M, Thomas Kevin A, Wilson Scott C
Department of Orthopaedic Surgery, Louisiana State University School of Medicine, New Orleans, LA, USA.
Clin Orthop Relat Res. 2003 Jun(411):296-304. doi: 10.1097/01.blo.0000069895.31220.e8.
Successful incorporation of massive allografts for the treatment of bone deficiency demands maximizing biologic and mechanical factors. These factors have yet to be mastered, as evidenced by the 8% to 17% nonunion and the 5% to 20% fracture rate. The current study addresses the allograft incorporation process by examining the three construct geometries: transverse, step-cut, and sigmoid. Specimens were plated and mounted on a mechanical testing machine. A rotational displacement was applied, and torsional stiffness (N-m/ degrees ), maximum torque (N-m), and maximum displacement ( degrees ) were calculated. The sigmoid osteotomies had a torsional stiffness of 1.90 +/- 0.68 N-m/ degrees and maximum torque of 18.85 +/- 6.63 N-m versus 0.99 +/- N-m/ degrees and 14.48 +/- 2.15 N-m for the transverse osteotomies; and a maximum angular displacement of 11.60 degrees +/- 1.78 degrees versus 5.73 degrees +/- 1.6 degrees for the step-cut osteotomies. The step-cut osteotomies consistently failed at the step-cut corners, which acted as stress risers. Computer-aided solid modeling of the contact surfaces showed that the step and sigmoid osteotomy areas were 74% and 44%, respectively, larger than the transverse osteotomy. The sigmoid osteotomy, created with a template and pneumatic drill, seems to offer a mechanical advantage over the transverse and step-cut osteotomies by increasing stability and contact surface area relative to the transverse osteotomy but reducing the stress-riser effect of the step-cut osteotomy.
成功植入大块异体骨治疗骨缺损需要最大限度地发挥生物学和力学因素的作用。这些因素尚未得到很好的掌控,8%至17%的不愈合率以及5%至20%的骨折率就证明了这一点。当前的研究通过检查三种结构几何形状:横向、阶梯状和乙状结肠形,来探讨异体骨的植入过程。将标本进行钢板固定并安装在机械测试机上。施加旋转位移,并计算扭转刚度(N-m/度)、最大扭矩(N-m)和最大位移(度)。乙状结肠形截骨术的扭转刚度为1.90±±0.68 N-m/度,最大扭矩为18.85±±6.63 N-m,而横向截骨术分别为0.99±±N-m/度和l4.48±±2.15 N-m;阶梯状截骨术的最大角位移为11.60度±±1.78度,而阶梯状截骨术为l5.73度±±1.6度。阶梯状截骨术总是在充当应力集中源的阶梯状拐角处发生失效。接触表面的计算机辅助实体建模显示,阶梯状和乙状结肠形截骨区域分别比横向截骨区域大74%和44%。用模板和气动钻制作的乙状结肠形截骨术,相对于横向和阶梯状截骨术似乎具有力学优势,因为它相对于横向截骨术增加了稳定性和接触表面积,但减少了阶梯状截骨术的应力集中效应。