Dziewas Rainer, Kuhlenbäumer Gregor, Okegwo Angelika, Lüdemann Peter
Department of Neurology, University Hospital Münster, Münster, Germany.
Mov Disord. 2003 Jun;18(6):718-22. doi: 10.1002/mds.10435.
Painful legs and moving toes (PLMT) is a rare syndrome which is characterised by involuntary movements of the toes and pain in the legs. We report on a mother and her daughter who both presented with involuntary movements of the toes similar to those seen in PLMT but without any associated pain. Neurological examination revealed intermittent 0.3 to 0.5-Hz flexion and extension of the toes and ankles of the right foot in the mother, and of both feet in the daughter. In both patients, the movements appeared during periods of rest that were uncorrelated with the time of day. Diagnostic work-up gave no evidence of radiculopathy or of focal neuropathy. Overnight polysomnography documented that movements of the toes and feet occurred only before sleep onset and during periods of nocturnal awakening or arousals. Because the movements observed in our patients were similar to those seen in patients with PLMT, we diagnosed an abortive form of this syndrome, which already has got the naming "painless legs and moving toes." The occurrence in a mother and her daughter may point to a hereditary component of this disorder.
痛性腿部与活动脚趾综合征（PLMT）是一种罕见的综合征，其特征为脚趾的不自主运动和腿部疼痛。我们报告了一位母亲和她的女儿，她们均表现出与PLMT中所见类似的脚趾不自主运动，但没有任何相关疼痛。神经学检查发现，母亲右脚的脚趾和脚踝有间歇性的0.3至0.5赫兹屈伸，女儿双脚有此现象。在两名患者中，这些运动均出现在休息期间，与一天中的时间无关。诊断检查未发现神经根病或局灶性神经病的证据。夜间多导睡眠图记录显示，脚趾和脚部的运动仅在入睡之前以及夜间觉醒或唤醒期间出现。由于我们患者中观察到的运动与PLMT患者中所见的运动相似，我们诊断为该综合征的一种顿挫型，其已被命名为“无痛性腿部与活动脚趾”。母亲和女儿均患病可能表明该疾病存在遗传因素。
