Abrahám György, Légrády Péter
Szegedi Tudományegyetem Szent-Györgyi Albert Orvos- és Gyógyszerésztudományi Centrum, Altalános Orvostudományi Kar, I. Belgyógyászati Klinika, Szeged.
Orv Hetil. 2003 May 4;144(18 Suppl 1):892-5.
The dysfunction of the renin-angiotensin-aldosterone system and its inhibition is a powerful therapeutic tool in the treatment of cardiovascular diseases. This system is a very ancient and sensitive mechanism, which reacts very much to the impacts from the environment. The system can be inhibited through four different ways; in the practice ACE inhibitors and ARBs are used mostly. Other--also beneficial--drugs might cause the over stimulation of the system. The inhibition of the RAAS system have significant impact on reduction in cardiovascular morbidity and mortality and have been shown convincingly additional benefits comparing to other treatments.
肾素-血管紧张素-醛固酮系统功能障碍及其抑制是治疗心血管疾病的有力治疗手段。该系统是一种非常古老且敏感的机制,对环境影响反应很大。该系统可通过四种不同方式被抑制;在实践中,主要使用的是ACE抑制剂和ARB。其他——同样有益的——药物可能会导致该系统过度刺激。抑制RAAS系统对降低心血管发病率和死亡率有显著影响,并且与其他治疗方法相比已被令人信服地证明有额外益处。