Hayward C, Killen J D, Taylor C B
Department of Psychiatry, Stanford University, Stanford, CA, USA.
Psychol Med. 2003 May;33(4):733-8. doi: 10.1017/s0033291702006955.
The purpose of this study was to evaluate the clinical correlates of agoraphobic fear and avoidance and panic disorder in a non-clinical sample of adolescents.
In a sample of 2365 high school students, combined data from a questionnaire and a structured clinical interview were used to classify subjects with agoraphobic fear and avoidance. Panic symptoms, major depression, childhood separation anxiety disorder, anxiety sensitivity and negative affectivity were also assessed.
Fifteen subjects met study criteria for agoraphobic fear and avoidance in the past year. Only three (20%) of those with agoraphobia symptoms reported histories of panic attacks and there was no overlap between those with agoraphobic fear and avoidance and the 12 subjects who met DSM-III-R criteria for panic disorder. However, subjects with agoraphobia symptoms and those with panic disorder reported similar levels of anxiety sensitivity and negative affectivity. Childhood separation anxiety disorder was more common among those with agoraphobic fear and avoidance compared to those without.
Agoraphobic avoidance is rare in non-clinical samples of adolescents and usually not associated with panic attacks. However, adolescents with agoraphobia symptoms and those with panic disorder have similar clinical correlates consistent with a panic/agoraphobia spectrum model.
本研究旨在评估青少年非临床样本中广场恐惧症的恐惧与回避及惊恐障碍的临床相关性。
在2365名高中生样本中,结合问卷调查和结构化临床访谈的数据对有广场恐惧症恐惧与回避症状的受试者进行分类。同时评估惊恐症状、重度抑郁、儿童期分离焦虑障碍、焦虑敏感性和负性情感。
在过去一年中,15名受试者符合广场恐惧症恐惧与回避的研究标准。有广场恐惧症症状的受试者中只有3人(20%)报告有惊恐发作史,且有广场恐惧症恐惧与回避症状的受试者与符合DSM-III-R惊恐障碍标准的12名受试者之间没有重叠。然而,有广场恐惧症症状的受试者和有惊恐障碍的受试者报告的焦虑敏感性和负性情感水平相似。与没有广场恐惧症恐惧与回避症状的受试者相比,儿童期分离焦虑障碍在有广场恐惧症恐惧与回避症状的受试者中更为常见。
广场恐惧症回避在青少年非临床样本中很少见,通常与惊恐发作无关。然而,有广场恐惧症症状的青少年和有惊恐障碍的青少年具有相似的临床相关性,这与惊恐/广场恐惧症谱系模型一致。