Loh Teck-Hiong, Yosipovitch Gil, Tay Yong-Kwang
National Skin Center, Singapore.
Pediatr Dermatol. 2003 May-Jun;20(3):195-8. doi: 10.1046/j.1525-1470.2003.20302.x.
We report six cases of palmar-plantar keratoderma of Unna Thost (PPKUT) associated with atopic dermatitis. All had typical features of PPKUT with diffuse, yellowish thickening on the palms and soles with a well-defined erythematous rim of demarcation on the sides associated with palmar-plantar hyperhidrosis. The changes were obvious since birth or arose during early life, and were persistent. We believe that the association between the two disorders is not coincidental but an underrecognized entity that may shed light on the underlying pathogenesis of these two conditions.
我们报告了6例与特应性皮炎相关的尤纳 - 托斯特掌跖角化病（PPKUT）。所有患者均具有PPKUT的典型特征，手掌和脚底弥漫性、淡黄色增厚，两侧有界限清晰的红斑分界边缘，伴有掌跖多汗症。这些变化自出生起就很明显或在早年出现，且持续存在。我们认为这两种疾病之间的关联并非偶然，而是一种未被充分认识的实体，可能有助于揭示这两种病症的潜在发病机制。
