Piazza Fabio, Frisina Antonio, Gandolfi Angelo, Quaranta Nicola, Zini Carlo
Department of ENT, Otology, Neurotology, and Skull Base Surgery, University of Parma, Italy.
Ear Nose Throat J. 2003 May;82(5):374-8.
The wide availability of gadolinium-enhanced magnetic resonance imaging (MRI-Gd) has led to the discovery of an increasing number of small and less symptomatic acoustic neuromas in elderly patients. We conducted a retrospective study in order to obtain data on outcomes and complications associated with different management strategies that would be useful in establishing a management guideline. We identified 44 patients aged 65 to 77 years with acoustic neuromas who had been managed with either surgery or simple observation with MRI-Gd imaging. Of the entire group, 36 patients had tumors larger than 1 cm, and they underwent surgery (most via the translabyrinthine approach). Complete removal of the tumor was achieved in 34 of these patients (94.4%). At the 1-year follow-up, grade VI facial nerve paralysis was evident in only two of 35 evaluable patients (5.7%). Postsurgical complications occurred in five patients (13.9%), including one death. The remaining eight patients had tumors 1 cm or smaller, and they were managed with periodic MRI-Gd scanning. At the 5-year follow-up, no tumor growth was seen in six of these patients. The other two patients exhibited a tumor growth rate of less than 2 mm per year. No patient in the observation group required surgical intervention.
钆增强磁共振成像(MRI-Gd)的广泛应用使得在老年患者中发现越来越多较小且症状较轻的听神经瘤。我们进行了一项回顾性研究,以获取与不同管理策略相关的结果和并发症数据,这将有助于制定管理指南。我们确定了44例年龄在65至77岁之间的听神经瘤患者,他们接受了手术治疗或仅通过MRI-Gd成像进行简单观察。在整个组中,36例患者的肿瘤大于1厘米,他们接受了手术(大多数通过经迷路入路)。其中34例患者(94.4%)实现了肿瘤的完全切除。在1年随访时,35例可评估患者中仅有2例(5.7%)出现了Ⅵ级面神经麻痹。5例患者(13.9%)发生了术后并发症,包括1例死亡。其余8例患者的肿瘤为1厘米或更小,他们接受了定期的MRI-Gd扫描。在5年随访时,这些患者中有6例未见肿瘤生长。另外2例患者的肿瘤生长速度小于每年2毫米。观察组中没有患者需要手术干预。