Vaillo Vinagre Agustín, Gutiérrez Martín Antonia, Pérez Barrios Andrés, Alberti Masgrau Nuria, Ballestín Carcavilla Claudio, De Agustín De Agustín Pedro
Cytology Unit, Department of Pathology, University Hospital 12 de Octubre, Ctra Andalucía Km. 5.400, Madrid, Spain.
Acta Cytol. 2003 May-Jun;47(3):485-9. doi: 10.1159/000326556.
Neurothekeoma (NT) is a rare, benign neoplasm of soft parts with a distinctive histologic appearance. To our knowledge, the cytologic findings have not been described before. We present a case of NT with the cytologic features on fine needle aspiration cytology (FNAC).
A 54-year-old female presented with a circumscribed nodule in the left breast. The lesion was evaluated by FNAC. The smears showed an abundant, metachromatic, myxoid matrix with fusiform and epithelioid cells, some binucleated or multinucleated, loose or in groups and sometimes forming concentric whorls. The lesion was removed, and the diagnosis of NT was made after histopathologic study.
NT is an extremely rare neoplasm in the mammary region. Fusiform and epithelioid cells arranged in concentric whorls in a myxoid tumor of soft tissue are a distinctive characteristic of this neoplasm and can suggest the diagnosis.
神经鞘黏液瘤(NT)是一种罕见的软组织良性肿瘤,具有独特的组织学表现。据我们所知,此前尚未描述过其细胞学表现。我们报告一例经细针穿刺细胞学检查(FNAC)具有细胞学特征的NT病例。
一名54岁女性,左乳出现一个边界清晰的结节。通过FNAC对该病变进行评估。涂片显示有丰富的异染性黏液样基质,伴有梭形和上皮样细胞,部分为双核或多核,细胞松散或成簇,有时形成同心性漩涡状结构。病变切除后,经组织病理学研究确诊为NT。
NT在乳腺区域极为罕见。软组织黏液样肿瘤中呈同心性漩涡状排列的梭形和上皮样细胞是该肿瘤的一个独特特征,可提示诊断。