Lou Meei-Fang, Dai Yu-Tzu, Huang Guey-Shiun, Yu Po-Jui
School of Nursing, College of Medicine, National Taiwan University, No. 1 Sec. 1 Jen-Ai Road, Taipei 100, Taiwan, ROC.
J Clin Nurs. 2003 Jul;12(4):579-88. doi: 10.1046/j.1365-2702.2003.00753.x.
The purpose of the study was to describe variations in cognitive/behavioural changes during the course of delirium among older Taiwanese patients after elective surgery. A total of 106 patients assessed four times (admission, onset of delirium, delirium day 3 and delirium day 5) by the Mini Mental State Examination (MMSE) were included in the analysis to understand the neurocognitive/behaviour change during the course of delirium. Repeated measures anova was used to analyse within-subject differences across these four time points for those who became delirious and those who did not. The findings showed that patients who experienced delirium had significantly (P < 0.01) lower MMSE scores than non-delirious patients. Scores for the delirious group were also significantly different across the four assessments (P < 0.01) within the group. The subscales of orientation to time, orientation to place, registration and recall were the major changes from time 1 (admission assessment) to time 2 (onset of delirium) for delirious patients. When scores for time 4 (delirium day 5) and time 1 (admission assessment) were compared, the subscales of orientation to time, orientation to place and visual construction showed the least improvement among the subscales at time 4. The findings of the study suggest that mental status assessments are important during the patient's admission and hospital stay. The repeated assessments can be incorporated into routine nursing care so that problems can be detected and appropriate nursing care implemented.
本研究的目的是描述台湾老年患者择期手术后谵妄过程中认知/行为变化的差异。共有106例患者通过简易精神状态检查表(MMSE)在四个时间点(入院时、谵妄发作时、谵妄第3天和谵妄第5天)进行评估,纳入分析以了解谵妄过程中的神经认知/行为变化。对于发生谵妄的患者和未发生谵妄的患者,采用重复测量方差分析来分析这四个时间点的个体内差异。研究结果显示,经历谵妄的患者MMSE评分显著低于未发生谵妄的患者(P<0.01)。谵妄组在这四项评估中的评分在组内也有显著差异(P<0.01)。对于发生谵妄的患者,从时间1(入院评估)到时间2(谵妄发作),时间定向、地点定向、登记和回忆等分量表有主要变化。当比较时间4(谵妄第5天)和时间1(入院评估)的评分时,时间定向、地点定向和视觉构建等分量表在时间4的各分量表中改善最少。该研究结果表明,在患者入院和住院期间进行精神状态评估很重要。重复评估可纳入常规护理,以便发现问题并实施适当的护理。