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癫痫发作后胼胝体压部的扩散加权成像异常。

Diffusion-weighted imaging abnormalities in the splenium after seizures.

作者信息

Oster Joel, Doherty Colin, Grant P Ellen, Simon Mirela, Cole Andrew J

机构信息

Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.

出版信息

Epilepsia. 2003 Jun;44(6):852-4. doi: 10.1046/j.1528-1157.2003.40902.x.

Abstract

PURPOSE

Transient increased T2 signal in the splenium of the corpus callosum after seizures has been reported and sometimes attributed to a postulated toxicity of anticonvulsant medications (AEDs).

METHODS

We describe two patients with bitemporal epilepsy.

RESULTS

Transiently increased T2 signal (in one) and decreased apparent diffusion coefficient (ADC) (in both) in the splenium appeared to be related directly to acute seizures.

CONCLUSIONS

These cases illustrate an unusual acute postictal imaging finding, highlight involvement of an important commissural pathway, and suggest that seizures per se, and not their treatment, are the cause of transient white-matter abnormalities in these cases.

摘要

目的

已有报道称癫痫发作后胼胝体压部T2信号短暂增强,有时归因于抗惊厥药物(AEDs)的假定毒性。

方法

我们描述了两名双颞叶癫痫患者。

结果

压部T2信号短暂增强(1例)和表观扩散系数(ADC)降低(2例)似乎与急性癫痫发作直接相关。

结论

这些病例说明了一种不寻常的急性发作后影像学表现,突出了重要连合通路的受累情况,并表明在这些病例中,癫痫发作本身而非其治疗是短暂性白质异常的原因。

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