正常大鼠和糖尿病大鼠完整肝细胞的脂肪生成
Lipogenesis by intact hepatocytes from normal and diabetic rats.
作者信息
Raghupathy E, Orthlieb C, Abraham S
出版信息
Lipids. 1975 Nov;10(11):653-5. doi: 10.1007/BF02532756.
PMID:127915
Abstract
Intact hepatocytes isolated from livers of diabetic rats demonstrate the characteristic decreased lipogenic capacities as compared to normal. Administration of insulin to diabetic rats restores these capacities to near normal levels. The results emphasize the potential that the hepatocyte system has for the study of hormonal regulation of lipogenesis.
摘要
与正常大鼠相比，从糖尿病大鼠肝脏分离出的完整肝细胞表现出典型的脂肪生成能力下降。给糖尿病大鼠注射胰岛素可使这些能力恢复到接近正常水平。这些结果强调了肝细胞系统在研究脂肪生成激素调节方面的潜力。
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